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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCM1 All Species: 9.09
Human Site: S1437 Identified Species: 18.18
UniProt: Q15154 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15154 NP_006188.3 2024 228485 S1437 V S R H I S E S H E K G E N V
Chimpanzee Pan troglodytes XP_001143666 2024 228648 S1437 V S R H I S E S H E K G E N V
Rhesus Macaque Macaca mulatta XP_001098130 2024 228669 S1437 V S R H I S E S H E K G E N V
Dog Lupus familis XP_856471 2034 229150 H1440 T R H I S E N H E K E G E N V
Cat Felis silvestris
Mouse Mus musculus Q9R0L6 2025 228814 D1435 S R H I S E S D E R E G E N V
Rat Rattus norvegicus NP_112338 2026 228715 D1435 S R H I S E S D E K E G E N I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508627 1158 129340 Q618 R S E G S E T Q G T P Q R S R
Chicken Gallus gallus Q8AV28 1904 212706 N1343 V T R H L S E N N E K G R C I
Frog Xenopus laevis Q9PVV4 2031 227849 A1471 R H V S E G N A K K H E T C T
Zebra Danio Brachydanio rerio NP_001108595 2018 226056 E1461 T E K S V A D E Q A S S L G P
Tiger Blowfish Takifugu rubipres NP_001027776 2075 229594 R1518 S L Q D I V T R H L T E K N A
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786223 2256 248984 A1704 M P A W M N F A G S E Q T P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.1 91.4 N.A. 88.7 88.5 N.A. 34.1 67.5 59.4 52.6 47.8 N.A. N.A. N.A. 26.1
Protein Similarity: 100 99.5 98.5 95.1 N.A. 93.4 93.2 N.A. 43.6 77.3 73.5 67.9 64.1 N.A. N.A. N.A. 45.7
P-Site Identity: 100 100 100 26.6 N.A. 26.6 20 N.A. 6.6 53.3 0 0 20 N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 40 N.A. 33.3 40 N.A. 13.3 86.6 13.3 26.6 33.3 N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 9 0 17 0 9 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % C
% Asp: 0 0 0 9 0 0 9 17 0 0 0 0 0 0 0 % D
% Glu: 0 9 9 0 9 34 34 9 25 34 34 17 50 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 9 0 0 17 0 0 59 0 9 0 % G
% His: 0 9 25 34 0 0 0 9 34 0 9 0 0 0 0 % H
% Ile: 0 0 0 25 34 0 0 0 0 0 0 0 0 0 17 % I
% Lys: 0 0 9 0 0 0 0 0 9 25 34 0 9 0 0 % K
% Leu: 0 9 0 0 9 0 0 0 0 9 0 0 9 0 0 % L
% Met: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 17 9 9 0 0 0 0 59 0 % N
% Pro: 0 9 0 0 0 0 0 0 0 0 9 0 0 9 9 % P
% Gln: 0 0 9 0 0 0 0 9 9 0 0 17 0 0 0 % Q
% Arg: 17 25 34 0 0 0 0 9 0 9 0 0 17 0 9 % R
% Ser: 25 34 0 17 34 34 17 25 0 9 9 9 0 9 9 % S
% Thr: 17 9 0 0 0 0 17 0 0 9 9 0 17 0 9 % T
% Val: 34 0 9 0 9 9 0 0 0 0 0 0 0 0 42 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _