Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCM1 All Species: 27.58
Human Site: S1768 Identified Species: 55.15
UniProt: Q15154 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15154 NP_006188.3 2024 228485 S1768 K N V R S D I S D Q E E D E E
Chimpanzee Pan troglodytes XP_001143666 2024 228648 S1768 K N V R S D I S D Q E E D E E
Rhesus Macaque Macaca mulatta XP_001098130 2024 228669 S1768 K N I R S D I S D Q E E D E E
Dog Lupus familis XP_856471 2034 229150 S1773 K N V R S D V S D Q E E D E E
Cat Felis silvestris
Mouse Mus musculus Q9R0L6 2025 228814 S1769 K N V R S D V S D Q E E D E E
Rat Rattus norvegicus NP_112338 2026 228715 S1769 K N V R S D V S D Q E E D E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508627 1158 129340 G926 S S G Q D T S G K T E H V A F
Chicken Gallus gallus Q8AV28 1904 212706 A1663 E S E S G P V A I S L S K A E
Frog Xenopus laevis Q9PVV4 2031 227849 S1789 N F D A E V L S G K S D I S E
Zebra Danio Brachydanio rerio NP_001108595 2018 226056 S1785 K E K E A Q S S E A S E V E E
Tiger Blowfish Takifugu rubipres NP_001027776 2075 229594 S1833 L Q E F Y Y Q S E K K S S R S
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786223 2256 248984 G2018 R F E E E E L G N T R D D M F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.1 91.4 N.A. 88.7 88.5 N.A. 34.1 67.5 59.4 52.6 47.8 N.A. N.A. N.A. 26.1
Protein Similarity: 100 99.5 98.5 95.1 N.A. 93.4 93.2 N.A. 43.6 77.3 73.5 67.9 64.1 N.A. N.A. N.A. 45.7
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 6.6 6.6 13.3 33.3 6.6 N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 33.3 33.3 46.6 26.6 N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 9 0 0 9 0 9 0 0 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 9 50 0 0 50 0 0 17 59 0 0 % D
% Glu: 9 9 25 17 17 9 0 0 17 0 59 59 0 59 75 % E
% Phe: 0 17 0 9 0 0 0 0 0 0 0 0 0 0 17 % F
% Gly: 0 0 9 0 9 0 0 17 9 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 9 0 0 0 25 0 9 0 0 0 9 0 0 % I
% Lys: 59 0 9 0 0 0 0 0 9 17 9 0 9 0 0 % K
% Leu: 9 0 0 0 0 0 17 0 0 0 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 9 50 0 0 0 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 9 0 9 9 0 0 50 0 0 0 0 0 % Q
% Arg: 9 0 0 50 0 0 0 0 0 0 9 0 0 9 0 % R
% Ser: 9 17 0 9 50 0 17 75 0 9 17 17 9 9 9 % S
% Thr: 0 0 0 0 0 9 0 0 0 17 0 0 0 0 0 % T
% Val: 0 0 42 0 0 9 34 0 0 0 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _