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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCM1 All Species: 20.3
Human Site: S542 Identified Species: 40.61
UniProt: Q15154 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15154 NP_006188.3 2024 228485 S542 Y D S E H E N S E P V T N I R
Chimpanzee Pan troglodytes XP_001143666 2024 228648 S542 Y D S E H E N S E P V T N I R
Rhesus Macaque Macaca mulatta XP_001098130 2024 228669 S542 Y D S E H E N S E P V T N I R
Dog Lupus familis XP_856471 2034 229150 P543 Y D S E H E N P E P V T N I R
Cat Felis silvestris
Mouse Mus musculus Q9R0L6 2025 228814 S547 Y D S E H E N S E P V T N I R
Rat Rattus norvegicus NP_112338 2026 228715 S547 Y D S E H E H S E P V T N I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508627 1158 129340
Chicken Gallus gallus Q8AV28 1904 212706 T497 R D G R H L N T D C E I N N R
Frog Xenopus laevis Q9PVV4 2031 227849 A579 Y D S E Q E D A E P T T N I R
Zebra Danio Brachydanio rerio NP_001108595 2018 226056 P569 S E Q E N H E P V T N I R N P
Tiger Blowfish Takifugu rubipres NP_001027776 2075 229594 V627 E Q D N R H S V T N I R N P Q
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786223 2256 248984 L594 K K R Q M D D L L I Q L H A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.1 91.4 N.A. 88.7 88.5 N.A. 34.1 67.5 59.4 52.6 47.8 N.A. N.A. N.A. 26.1
Protein Similarity: 100 99.5 98.5 95.1 N.A. 93.4 93.2 N.A. 43.6 77.3 73.5 67.9 64.1 N.A. N.A. N.A. 45.7
P-Site Identity: 100 100 100 93.3 N.A. 100 93.3 N.A. 0 33.3 73.3 6.6 6.6 N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 0 46.6 86.6 20 26.6 N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 67 9 0 0 9 17 0 9 0 0 0 0 0 0 % D
% Glu: 9 9 0 67 0 59 9 0 59 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 59 17 9 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 9 17 0 59 0 % I
% Lys: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 9 0 9 9 0 0 9 0 0 9 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 9 0 50 0 0 9 9 0 75 17 0 % N
% Pro: 0 0 0 0 0 0 0 17 0 59 0 0 0 9 9 % P
% Gln: 0 9 9 9 9 0 0 0 0 0 9 0 0 0 9 % Q
% Arg: 9 0 9 9 9 0 0 0 0 0 0 9 9 0 67 % R
% Ser: 9 0 59 0 0 0 9 42 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 9 9 9 9 59 0 0 0 % T
% Val: 0 0 0 0 0 0 0 9 9 0 50 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _