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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCM1 All Species: 9.39
Human Site: S936 Identified Species: 18.79
UniProt: Q15154 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15154 NP_006188.3 2024 228485 S936 D N F S V C P S N S V N H N S
Chimpanzee Pan troglodytes XP_001143666 2024 228648 S936 D N F S V Y P S N S V N H N S
Rhesus Macaque Macaca mulatta XP_001098130 2024 228669 S936 D N F S V Y P S N S V N H N S
Dog Lupus familis XP_856471 2034 229150 P937 N D N F S M Y P P N S A N H N
Cat Felis silvestris
Mouse Mus musculus Q9R0L6 2025 228814 P934 D N F P I Y P P S M N Q N S Y
Rat Rattus norvegicus NP_112338 2026 228715 P934 D N F P M Y H P S M N Q N S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508627 1158 129340 L148 M D K L L G E L H T L R D Q H
Chicken Gallus gallus Q8AV28 1904 212706 N843 S F S A Y P N N Q I P E S V Y
Frog Xenopus laevis Q9PVV4 2031 227849 Q970 C E N N S Y P Q N S I R K T S
Zebra Danio Brachydanio rerio NP_001108595 2018 226056 S951 T D E R H A C S T Q K Q R N Y
Tiger Blowfish Takifugu rubipres NP_001027776 2075 229594 R1016 N Q S S Y S N R K N Q G S N R
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786223 2256 248984 D1087 T Y T I E S G D K P P S R R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.1 91.4 N.A. 88.7 88.5 N.A. 34.1 67.5 59.4 52.6 47.8 N.A. N.A. N.A. 26.1
Protein Similarity: 100 99.5 98.5 95.1 N.A. 93.4 93.2 N.A. 43.6 77.3 73.5 67.9 64.1 N.A. N.A. N.A. 45.7
P-Site Identity: 100 93.3 93.3 0 N.A. 26.6 20 N.A. 0 0 26.6 13.3 13.3 N.A. N.A. N.A. 0
P-Site Similarity: 100 93.3 93.3 40 N.A. 53.3 46.6 N.A. 33.3 13.3 40 20 26.6 N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 0 0 0 0 0 9 0 0 0 % A
% Cys: 9 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % C
% Asp: 42 25 0 0 0 0 0 9 0 0 0 0 9 0 0 % D
% Glu: 0 9 9 0 9 0 9 0 0 0 0 9 0 0 0 % E
% Phe: 0 9 42 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 9 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 0 9 0 9 0 9 0 0 0 25 9 9 % H
% Ile: 0 0 0 9 9 0 0 0 0 9 9 0 0 0 0 % I
% Lys: 0 0 9 0 0 0 0 0 17 0 9 0 9 0 0 % K
% Leu: 0 0 0 9 9 0 0 9 0 0 9 0 0 0 0 % L
% Met: 9 0 0 0 9 9 0 0 0 17 0 0 0 0 0 % M
% Asn: 17 42 17 9 0 0 17 9 34 17 17 25 25 42 9 % N
% Pro: 0 0 0 17 0 9 42 25 9 9 17 0 0 0 0 % P
% Gln: 0 9 0 0 0 0 0 9 9 9 9 25 0 9 0 % Q
% Arg: 0 0 0 9 0 0 0 9 0 0 0 17 17 9 17 % R
% Ser: 9 0 17 34 17 17 0 34 17 34 9 9 17 17 34 % S
% Thr: 17 0 9 0 0 0 0 0 9 9 0 0 0 9 0 % T
% Val: 0 0 0 0 25 0 0 0 0 0 25 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 17 42 9 0 0 0 0 0 0 0 34 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _