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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCM1 All Species: 10.61
Human Site: T158 Identified Species: 21.21
UniProt: Q15154 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15154 NP_006188.3 2024 228485 T158 N K S K D A S T S P P N R E T
Chimpanzee Pan troglodytes XP_001143666 2024 228648 T158 N K S K D A S T S P P N R E T
Rhesus Macaque Macaca mulatta XP_001098130 2024 228669 T158 N K S K D A S T S P P N R E T
Dog Lupus familis XP_856471 2034 229150 I158 N K S K D A A I S P P K R E M
Cat Felis silvestris
Mouse Mus musculus Q9R0L6 2025 228814 A158 N K S K D A T A S L P K R E M
Rat Rattus norvegicus NP_112338 2026 228715 A158 N K S K D A T A S L P K R E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508627 1158 129340
Chicken Gallus gallus Q8AV28 1904 212706 I158 L Q N G Q L S I Q E D G R G E
Frog Xenopus laevis Q9PVV4 2031 227849 S155 T N K E K S K S P P K R E A S
Zebra Danio Brachydanio rerio NP_001108595 2018 226056 K170 T S S T P G G K E H K K Q S P
Tiger Blowfish Takifugu rubipres NP_001027776 2075 229594 K176 P A I S Q E M K K Q G P G L R
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786223 2256 248984 R193 D R N K I V A R L M Q I R D Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.1 91.4 N.A. 88.7 88.5 N.A. 34.1 67.5 59.4 52.6 47.8 N.A. N.A. N.A. 26.1
Protein Similarity: 100 99.5 98.5 95.1 N.A. 93.4 93.2 N.A. 43.6 77.3 73.5 67.9 64.1 N.A. N.A. N.A. 45.7
P-Site Identity: 100 100 100 73.3 N.A. 66.6 73.3 N.A. 0 13.3 6.6 6.6 0 N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 80 N.A. 73.3 80 N.A. 0 26.6 33.3 13.3 0 N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 50 17 17 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 50 0 0 0 0 0 9 0 0 9 0 % D
% Glu: 0 0 0 9 0 9 0 0 9 9 0 0 9 50 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 9 9 0 0 0 9 9 9 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 9 0 9 0 0 17 0 0 0 9 0 0 0 % I
% Lys: 0 50 9 59 9 0 9 17 9 0 17 34 0 0 0 % K
% Leu: 9 0 0 0 0 9 0 0 9 17 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 17 % M
% Asn: 50 9 17 0 0 0 0 0 0 0 0 25 0 0 0 % N
% Pro: 9 0 0 0 9 0 0 0 9 42 50 9 0 0 9 % P
% Gln: 0 9 0 0 17 0 0 0 9 9 9 0 9 0 0 % Q
% Arg: 0 9 0 0 0 0 0 9 0 0 0 9 67 0 9 % R
% Ser: 0 9 59 9 0 9 34 9 50 0 0 0 0 9 9 % S
% Thr: 17 0 0 9 0 0 17 25 0 0 0 0 0 0 34 % T
% Val: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _