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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PON2
All Species:
25.45
Human Site:
T139
Identified Species:
70
UniProt:
Q15165
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15165
NP_000296.2
354
39398
T139
N
H
P
E
F
K
N
T
V
E
I
F
K
F
E
Chimpanzee
Pan troglodytes
XP_519211
355
39709
T140
N
H
P
D
A
K
S
T
V
E
L
F
K
F
Q
Rhesus Macaque
Macaca mulatta
XP_001095459
375
41456
T160
N
H
P
E
F
K
N
T
V
E
I
F
K
F
E
Dog
Lupus familis
XP_855576
268
30316
F57
F
K
N
T
V
E
I
F
K
F
E
E
E
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q62086
354
39599
T139
N
H
P
Q
F
K
S
T
V
E
I
F
K
F
Q
Rat
Rattus norvegicus
Q6AXM8
354
39599
T139
N
H
P
E
F
K
N
T
V
E
I
F
K
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90952
354
39390
T139
N
H
P
H
Q
K
S
T
V
E
L
F
K
F
M
Frog
Xenopus laevis
NP_001080649
357
40208
T141
N
H
P
L
Y
K
T
T
I
E
L
F
K
F
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01811
377
42472
Q150
I
N
A
H
P
N
H
Q
C
I
H
F
F
Q
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.9
90.4
70.9
N.A.
85.8
87.2
N.A.
N.A.
72.5
60.2
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
100
78.5
91.4
73.7
N.A.
92
92
N.A.
N.A.
82.7
77
N.A.
N.A.
N.A.
N.A.
41.6
N.A.
P-Site Identity:
100
66.6
100
0
N.A.
80
93.3
N.A.
N.A.
66.6
66.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
93.3
100
13.3
N.A.
100
100
N.A.
N.A.
80
86.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
34
0
12
0
0
0
78
12
12
12
12
34
% E
% Phe:
12
0
0
0
45
0
0
12
0
12
0
89
12
78
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
78
0
23
0
0
12
0
0
0
12
0
0
0
0
% H
% Ile:
12
0
0
0
0
0
12
0
12
12
45
0
0
0
12
% I
% Lys:
0
12
0
0
0
78
0
0
12
0
0
0
78
0
0
% K
% Leu:
0
0
0
12
0
0
0
0
0
0
34
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
78
12
12
0
0
12
34
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
78
0
12
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
12
12
0
0
12
0
0
0
0
0
12
34
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
12
0
0
12
78
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
67
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _