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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP2R5A All Species: 28.48
Human Site: S28 Identified Species: 48.21
UniProt: Q15172 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15172 NP_006234.1 486 56194 S28 V D G F T R K S V R K A Q R Q
Chimpanzee Pan troglodytes XP_001151388 673 75031 S254 V D G F T R K S V R K A Q R Q
Rhesus Macaque Macaca mulatta XP_001106979 628 70785 S188 V D G F T R K S V R K A Q R Q
Dog Lupus familis XP_547400 566 64736 S108 V D G F A R K S V R K A Q R Q
Cat Felis silvestris
Mouse Mus musculus Q6PD03 486 56328 S28 V D G F T R K S V R K A Q R Q
Rat Rattus norvegicus NP_001101361 486 56318 S28 V D G F T R K S V R K A Q R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509703 483 55774 A28 T R K S V R K A Q R Q K R S Q
Chicken Gallus gallus XP_419432 476 55266 S28 K A Q R Q K R S Q G S S Q F R
Frog Xenopus laevis NP_001086500 476 55192 S31 Q R R S Q G S S Q F R G Q G P
Zebra Danio Brachydanio rerio XP_690932 478 56125 Q28 A Q R Q R V C Q G S S Q F A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651569 524 59708 S28 K G K K S Q G S S R Y R N S Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780697 432 50137 Q28 K G K Q K K S Q G S S Q Y R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU89 510 58740 S66 G K S A A S D S G F K D G N L
Baker's Yeast Sacchar. cerevisiae P38903 757 85316 S122 S S T K K T S S R K G Q E Q S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.6 74.3 85.1 N.A. 97.7 97.9 N.A. 95 93.2 88 80 N.A. 66.7 N.A. N.A. 68.3
Protein Similarity: 100 66.1 74.5 85.1 N.A. 98.7 98.7 N.A. 97.5 95.8 94 88.8 N.A. 78 N.A. N.A. 78.8
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. 26.6 13.3 13.3 0 N.A. 20 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 46.6 40 20 0 N.A. 33.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 48.2 37.5 N.A.
Protein Similarity: N.A. N.A. N.A. 65.2 49.5 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 15 0 0 8 0 0 0 43 0 8 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 43 0 0 0 0 8 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 43 0 0 0 0 0 15 0 0 8 8 0 % F
% Gly: 8 15 43 0 0 8 8 0 22 8 8 8 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 22 8 22 15 15 15 50 0 0 8 50 8 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 8 8 8 15 15 8 0 15 22 0 8 22 58 8 58 % Q
% Arg: 0 15 15 8 8 50 8 0 8 58 8 8 8 50 8 % R
% Ser: 8 8 8 15 8 8 22 79 8 15 22 8 0 15 8 % S
% Thr: 8 0 8 0 36 8 0 0 0 0 0 0 0 0 0 % T
% Val: 43 0 0 0 8 8 0 0 43 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _