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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP2R5A All Species: 22.73
Human Site: S41 Identified Species: 38.46
UniProt: Q15172 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15172 NP_006234.1 486 56194 S41 R Q K R S Q G S S Q F R S Q G
Chimpanzee Pan troglodytes XP_001151388 673 75031 S267 R Q K R S Q G S S Q F R S Q G
Rhesus Macaque Macaca mulatta XP_001106979 628 70785 S201 R Q K R S Q G S S Q F R S Q G
Dog Lupus familis XP_547400 566 64736 S121 R Q K R S Q G S S Q F R S Q G
Cat Felis silvestris
Mouse Mus musculus Q6PD03 486 56328 S41 R Q K R S Q G S S Q F R S Q G
Rat Rattus norvegicus NP_001101361 486 56318 S41 R Q K R S Q G S S Q F R S Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509703 483 55774 R41 S Q G S S Q F R S Q S S Q A E
Chicken Gallus gallus XP_419432 476 55266 V41 F R S Q S S Q V E L S P L P Q
Frog Xenopus laevis NP_001086500 476 55192 P44 G P P V E L S P L P P L K D A
Zebra Danio Brachydanio rerio XP_690932 478 56125 A41 A V N S S R P A A P E I S A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651569 524 59708 Q41 S Q D V E L Q Q L P P L K A D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780697 432 50137 I41 R L S N N T E I Q Q L N L L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU89 510 58740 N79 N L K S S G N N N N N N N N G
Baker's Yeast Sacchar. cerevisiae P38903 757 85316 P135 Q S K Q S Q Q P S Q S Q K Q G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.6 74.3 85.1 N.A. 97.7 97.9 N.A. 95 93.2 88 80 N.A. 66.7 N.A. N.A. 68.3
Protein Similarity: 100 66.1 74.5 85.1 N.A. 98.7 98.7 N.A. 97.5 95.8 94 88.8 N.A. 78 N.A. N.A. 78.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 33.3 6.6 0 13.3 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 33.3 20 0 33.3 N.A. 6.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 48.2 37.5 N.A.
Protein Similarity: N.A. N.A. N.A. 65.2 49.5 N.A.
P-Site Identity: N.A. N.A. N.A. 20 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 8 8 0 0 0 0 22 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 8 % D
% Glu: 0 0 0 0 15 0 8 0 8 0 8 0 0 0 8 % E
% Phe: 8 0 0 0 0 0 8 0 0 0 43 0 0 0 0 % F
% Gly: 8 0 8 0 0 8 43 0 0 0 0 0 0 0 58 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % I
% Lys: 0 0 58 0 0 0 0 0 0 0 0 0 22 0 8 % K
% Leu: 0 15 0 0 0 15 0 0 15 8 8 15 15 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 8 8 8 0 8 8 8 8 8 15 8 8 0 % N
% Pro: 0 8 8 0 0 0 8 15 0 22 15 8 0 8 0 % P
% Gln: 8 58 0 15 0 58 22 8 8 65 0 8 8 50 8 % Q
% Arg: 50 8 0 43 0 8 0 8 0 0 0 43 0 0 0 % R
% Ser: 15 8 15 22 79 8 8 43 58 0 22 8 50 0 0 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % T
% Val: 0 8 0 15 0 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _