KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5A
All Species:
20.91
Human Site:
S478
Identified Species:
35.38
UniProt:
Q15172
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15172
NP_006234.1
486
56194
S478
N
S
A
Y
N
M
H
S
I
L
S
N
T
S
A
Chimpanzee
Pan troglodytes
XP_001151388
673
75031
E666
L
T
S
S
Y
K
A
E
R
Q
R
Y
L
I
F
Rhesus Macaque
Macaca mulatta
XP_001106979
628
70785
S620
N
S
A
Y
N
M
H
S
I
L
S
N
T
S
A
Dog
Lupus familis
XP_547400
566
64736
S558
N
S
A
Y
N
M
H
S
I
L
S
N
T
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD03
486
56328
S478
N
N
A
Y
N
M
H
S
I
R
S
S
T
S
A
Rat
Rattus norvegicus
NP_001101361
486
56318
S478
N
N
A
Y
N
M
H
S
I
L
S
N
T
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509703
483
55774
N475
N
S
A
H
N
V
L
N
A
H
N
T
T
S
A
Chicken
Gallus gallus
XP_419432
476
55266
L468
Q
N
S
T
H
N
V
L
N
A
H
N
T
S
A
Frog
Xenopus laevis
NP_001086500
476
55192
N468
N
P
A
L
C
V
Q
N
I
Q
N
N
A
S
A
Zebra Danio
Brachydanio rerio
XP_690932
478
56125
F470
N
N
R
H
D
I
Q
F
T
Y
N
N
N
N
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651569
524
59708
S498
S
N
S
G
S
S
G
S
L
S
S
G
G
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780697
432
50137
S425
L
F
D
E
L
T
T
S
Y
K
A
D
R
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
E503
A
T
W
K
R
L
E
E
L
G
V
R
K
A
S
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
E710
E
N
W
S
K
L
E
E
Y
V
K
N
L
R
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.6
74.3
85.1
N.A.
97.7
97.9
N.A.
95
93.2
88
80
N.A.
66.7
N.A.
N.A.
68.3
Protein Similarity:
100
66.1
74.5
85.1
N.A.
98.7
98.7
N.A.
97.5
95.8
94
88.8
N.A.
78
N.A.
N.A.
78.8
P-Site Identity:
100
0
100
93.3
N.A.
80
93.3
N.A.
46.6
26.6
40
13.3
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
100
93.3
N.A.
93.3
100
N.A.
73.3
46.6
60
53.3
N.A.
53.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.2
37.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.2
49.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
50
0
0
0
8
0
8
8
8
0
8
15
50
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
0
0
0
0
8
0
0
8
% D
% Glu:
8
0
0
8
0
0
15
22
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
8
0
0
8
0
0
8
0
8
8
0
8
% G
% His:
0
0
0
15
8
0
36
0
0
8
8
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
0
0
43
0
0
0
0
8
8
% I
% Lys:
0
0
0
8
8
8
0
0
0
8
8
0
8
0
8
% K
% Leu:
15
0
0
8
8
15
8
8
15
29
0
0
15
0
0
% L
% Met:
0
0
0
0
0
36
0
0
0
0
0
0
0
0
0
% M
% Asn:
58
43
0
0
43
8
0
15
8
0
22
58
8
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
15
0
0
15
0
0
0
8
0
% Q
% Arg:
0
0
8
0
8
0
0
0
8
8
8
8
8
8
0
% R
% Ser:
8
29
22
15
8
8
0
50
0
8
43
8
0
58
8
% S
% Thr:
0
15
0
8
0
8
8
0
8
0
0
8
50
0
0
% T
% Val:
0
0
0
0
0
15
8
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
36
8
0
0
0
15
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _