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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5A
All Species:
31.21
Human Site:
S89
Identified Species:
52.82
UniProt:
Q15172
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15172
NP_006234.1
486
56194
S89
F
D
F
M
D
S
V
S
D
L
K
S
K
E
I
Chimpanzee
Pan troglodytes
XP_001151388
673
75031
S315
F
D
F
M
D
S
V
S
D
L
K
S
K
E
I
Rhesus Macaque
Macaca mulatta
XP_001106979
628
70785
S249
F
D
F
M
D
S
V
S
D
L
K
S
K
E
I
Dog
Lupus familis
XP_547400
566
64736
S169
F
D
F
M
D
S
V
S
D
L
K
S
K
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD03
486
56328
S89
F
D
F
M
D
S
V
S
D
L
K
S
K
E
I
Rat
Rattus norvegicus
NP_001101361
486
56318
S89
F
D
F
M
D
S
V
S
D
L
K
S
K
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509703
483
55774
S85
F
D
F
M
D
S
V
S
D
L
K
S
K
E
I
Chicken
Gallus gallus
XP_419432
476
55266
K82
M
D
S
V
S
D
L
K
G
K
E
I
K
R
A
Frog
Xenopus laevis
NP_001086500
476
55192
K86
D
L
K
S
K
E
I
K
R
A
T
L
N
E
L
Zebra Danio
Brachydanio rerio
XP_690932
478
56125
T81
F
D
F
Y
D
T
V
T
D
L
K
S
K
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651569
524
59708
K81
P
V
T
D
L
K
G
K
E
I
K
R
A
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780697
432
50137
R81
M
D
A
V
S
E
L
R
G
K
E
I
K
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
K132
P
T
K
N
I
K
E
K
D
I
K
R
Q
T
L
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
Q313
N
D
P
S
F
D
I
Q
G
K
E
I
K
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.6
74.3
85.1
N.A.
97.7
97.9
N.A.
95
93.2
88
80
N.A.
66.7
N.A.
N.A.
68.3
Protein Similarity:
100
66.1
74.5
85.1
N.A.
98.7
98.7
N.A.
97.5
95.8
94
88.8
N.A.
78
N.A.
N.A.
78.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
13.3
6.6
73.3
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
33.3
20
86.6
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.2
37.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.2
49.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
8
0
0
8
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
79
0
8
58
15
0
0
65
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
15
8
0
8
0
22
0
0
65
0
% E
% Phe:
58
0
58
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
22
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
15
0
0
15
0
22
0
0
50
% I
% Lys:
0
0
15
0
8
15
0
29
0
22
72
0
79
0
0
% K
% Leu:
0
8
0
0
8
0
15
0
0
58
0
8
0
0
22
% L
% Met:
15
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
15
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
8
0
0
15
0
22
0
% R
% Ser:
0
0
8
15
15
50
0
50
0
0
0
58
0
0
8
% S
% Thr:
0
8
8
0
0
8
0
8
0
0
8
0
0
8
8
% T
% Val:
0
8
0
15
0
0
58
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _