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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP2R5B All Species: 10.61
Human Site: S13 Identified Species: 19.44
UniProt: Q15173 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15173 NP_006235.1 497 57393 S13 P P A S T P T S P S S P G L S
Chimpanzee Pan troglodytes XP_001151388 673 75031 A110 R E A R S A P A P P C P R L S
Rhesus Macaque Macaca mulatta XP_001118226 461 51935 L13 G G W G Q Q R L P W R L G G S
Dog Lupus familis XP_540876 497 57436 S13 P P A S T P T S P S S P G L S
Cat Felis silvestris
Mouse Mus musculus Q6PD03 486 56328 I15 A P V A C A A I S A S E K V D
Rat Rattus norvegicus NP_852044 497 57308 S13 P P A S T P T S P S S P G L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506784 467 54655 G16 P S V D K V D G F S R K S V R
Chicken Gallus gallus XP_419432 476 55266 G13 S A A E K V D G F T R K S V R
Frog Xenopus laevis NP_001086500 476 55192 V18 D G F T R K S V R K A Q R Q R
Zebra Danio Brachydanio rerio XP_690770 503 58484 P15 P P S S P S S P T T G F S V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780697 432 50137
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU89 510 58740 N45 S T S K S T D N G A A K S H A
Baker's Yeast Sacchar. cerevisiae P38903 757 85316 S110 S S R S S S V S R S G S S S T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.8 77 99.1 N.A. 68.8 98.9 N.A. 68.8 68.2 68 79.7 N.A. N.A. N.A. N.A. 62.9
Protein Similarity: 100 59.5 79.8 99.5 N.A. 82.9 99.4 N.A. 83 82 81.6 89.2 N.A. N.A. N.A. N.A. 75.8
P-Site Identity: 100 33.3 20 100 N.A. 13.3 100 N.A. 13.3 6.6 0 20 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 46.6 20 100 N.A. 33.3 100 N.A. 20 20 20 46.6 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 47.8 34.8 N.A.
Protein Similarity: N.A. N.A. N.A. 64.1 47.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 39 8 0 16 8 8 0 16 16 0 0 0 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 8 0 0 8 0 0 24 0 0 0 0 0 0 0 8 % D
% Glu: 0 8 0 8 0 0 0 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 16 0 0 8 0 0 0 % F
% Gly: 8 16 0 8 0 0 0 16 8 0 16 0 31 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 8 16 8 0 0 0 8 0 24 8 0 0 % K
% Leu: 0 0 0 0 0 0 0 8 0 0 0 8 0 31 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 39 39 0 0 8 24 8 8 39 8 0 31 0 0 8 % P
% Gln: 0 0 0 0 8 8 0 0 0 0 0 8 0 8 0 % Q
% Arg: 8 0 8 8 8 0 8 0 16 0 24 0 16 0 24 % R
% Ser: 24 16 16 39 24 16 16 31 8 39 31 8 39 8 39 % S
% Thr: 0 8 0 8 24 8 24 0 8 16 0 0 0 0 8 % T
% Val: 0 0 16 0 0 16 8 8 0 0 0 0 0 31 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _