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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5B
All Species:
13.64
Human Site:
S15
Identified Species:
25
UniProt:
Q15173
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15173
NP_006235.1
497
57393
S15
A
S
T
P
T
S
P
S
S
P
G
L
S
P
V
Chimpanzee
Pan troglodytes
XP_001151388
673
75031
P112
A
R
S
A
P
A
P
P
C
P
R
L
S
C
L
Rhesus Macaque
Macaca mulatta
XP_001118226
461
51935
W15
W
G
Q
Q
R
L
P
W
R
L
G
G
S
V
P
Dog
Lupus familis
XP_540876
497
57436
S15
A
S
T
P
T
S
P
S
S
P
G
L
S
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD03
486
56328
A17
V
A
C
A
A
I
S
A
S
E
K
V
D
G
F
Rat
Rattus norvegicus
NP_852044
497
57308
S15
A
S
T
P
T
S
P
S
S
P
G
L
S
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506784
467
54655
S18
V
D
K
V
D
G
F
S
R
K
S
V
R
K
A
Chicken
Gallus gallus
XP_419432
476
55266
T15
A
E
K
V
D
G
F
T
R
K
S
V
R
K
A
Frog
Xenopus laevis
NP_001086500
476
55192
K20
F
T
R
K
S
V
R
K
A
Q
R
Q
R
R
S
Zebra Danio
Brachydanio rerio
XP_690770
503
58484
T17
S
S
P
S
S
P
T
T
G
F
S
V
P
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780697
432
50137
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
A47
S
K
S
T
D
N
G
A
A
K
S
H
A
K
N
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
S112
R
S
S
S
V
S
R
S
G
S
S
S
T
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.8
77
99.1
N.A.
68.8
98.9
N.A.
68.8
68.2
68
79.7
N.A.
N.A.
N.A.
N.A.
62.9
Protein Similarity:
100
59.5
79.8
99.5
N.A.
82.9
99.4
N.A.
83
82
81.6
89.2
N.A.
N.A.
N.A.
N.A.
75.8
P-Site Identity:
100
33.3
20
100
N.A.
6.6
100
N.A.
6.6
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
53.3
20
100
N.A.
26.6
100
N.A.
13.3
20
20
33.3
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.8
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.1
47.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
8
0
16
8
8
0
16
16
0
0
0
8
0
24
% A
% Cys:
0
0
8
0
0
0
0
0
8
0
0
0
0
8
0
% C
% Asp:
0
8
0
0
24
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
16
0
0
8
0
0
0
0
8
% F
% Gly:
0
8
0
0
0
16
8
0
16
0
31
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
16
8
0
0
0
8
0
24
8
0
0
31
8
% K
% Leu:
0
0
0
0
0
8
0
0
0
8
0
31
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
8
24
8
8
39
8
0
31
0
0
8
24
8
% P
% Gln:
0
0
8
8
0
0
0
0
0
8
0
8
0
0
0
% Q
% Arg:
8
8
8
0
8
0
16
0
24
0
16
0
24
8
0
% R
% Ser:
16
39
24
16
16
31
8
39
31
8
39
8
39
8
8
% S
% Thr:
0
8
24
8
24
0
8
16
0
0
0
0
8
0
0
% T
% Val:
16
0
0
16
8
8
0
0
0
0
0
31
0
8
24
% V
% Trp:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _