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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP2R5B All Species: 15.45
Human Site: S32 Identified Species: 28.33
UniProt: Q15173 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15173 NP_006235.1 497 57393 S32 P D K V D G F S R R S L R R A
Chimpanzee Pan troglodytes XP_001151388 673 75031 A129 G L S S T R S A R P E S T T S
Rhesus Macaque Macaca mulatta XP_001118226 461 51935 G32 A G A A G G A G V Q A Q D A L
Dog Lupus familis XP_540876 497 57436 S32 P D K V D G F S R R S L R R A
Cat Felis silvestris
Mouse Mus musculus Q6PD03 486 56328 R34 K S V R K A Q R Q K R S Q G S
Rat Rattus norvegicus NP_852044 497 57308 S32 P D K V D G F S R R S L R R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506784 467 54655 Q35 K R S Q S S S Q F R S Q G K P
Chicken Gallus gallus XP_419432 476 55266 S32 Q K R S Q G S S Q F R S Q S S
Frog Xenopus laevis NP_001086500 476 55192 G37 S S Q F R G Q G P P V E L S P
Zebra Danio Brachydanio rerio XP_690770 503 58484 S34 V D G F P R R S M R R A R Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780697 432 50137 R20 P F A K K S L R K G K Q K K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU89 510 58740 S64 P A G K S A A S D S G F K D G
Baker's Yeast Sacchar. cerevisiae P38903 757 85316 S129 S R K G Q E Q S K Q S Q Q P S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.8 77 99.1 N.A. 68.8 98.9 N.A. 68.8 68.2 68 79.7 N.A. N.A. N.A. N.A. 62.9
Protein Similarity: 100 59.5 79.8 99.5 N.A. 82.9 99.4 N.A. 83 82 81.6 89.2 N.A. N.A. N.A. N.A. 75.8
P-Site Identity: 100 6.6 6.6 100 N.A. 0 100 N.A. 13.3 13.3 6.6 26.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 20 20 100 N.A. 26.6 100 N.A. 20 40 13.3 33.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 47.8 34.8 N.A.
Protein Similarity: N.A. N.A. N.A. 64.1 47.6 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 16 8 0 16 16 8 0 0 8 8 0 8 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 31 0 0 24 0 0 0 8 0 0 0 8 8 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 8 8 0 0 0 % E
% Phe: 0 8 0 16 0 0 24 0 8 8 0 8 0 0 0 % F
% Gly: 8 8 16 8 8 47 0 16 0 8 8 0 8 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 16 8 31 16 16 0 0 0 16 8 8 0 16 16 0 % K
% Leu: 0 8 0 0 0 0 8 0 0 0 0 24 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 39 0 0 0 8 0 0 0 8 16 0 0 0 8 16 % P
% Gln: 8 0 8 8 16 0 24 8 16 16 0 31 24 8 0 % Q
% Arg: 0 16 8 8 8 16 8 16 31 39 24 0 31 24 8 % R
% Ser: 16 16 16 16 16 16 24 54 0 8 39 24 0 16 39 % S
% Thr: 0 0 0 0 8 0 0 0 0 0 0 0 8 8 0 % T
% Val: 8 0 8 24 0 0 0 0 8 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _