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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5B
All Species:
13.03
Human Site:
S48
Identified Species:
23.89
UniProt:
Q15173
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15173
NP_006235.1
497
57393
S48
P
R
R
S
H
S
S
S
Q
F
R
Y
Q
S
N
Chimpanzee
Pan troglodytes
XP_001151388
673
75031
P145
P
P
S
A
P
A
L
P
S
V
S
P
G
S
S
Rhesus Macaque
Macaca mulatta
XP_001118226
461
51935
E48
S
P
D
V
P
A
S
E
L
H
E
L
L
S
R
Dog
Lupus familis
XP_540876
497
57436
S48
P
R
R
S
H
S
S
S
Q
F
R
Y
Q
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD03
486
56328
Q50
Q
F
R
S
Q
G
S
Q
A
E
L
H
P
L
P
Rat
Rattus norvegicus
NP_852044
497
57308
S48
P
R
R
S
H
S
S
S
Q
F
R
Y
Q
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506784
467
54655
L51
E
L
T
P
L
P
L
L
K
D
V
A
S
S
E
Chicken
Gallus gallus
XP_419432
476
55266
Q48
V
E
L
S
P
L
P
Q
L
K
D
A
T
S
N
Frog
Xenopus laevis
NP_001086500
476
55192
S53
P
P
L
K
D
A
T
S
N
E
Q
Q
D
L
F
Zebra Danio
Brachydanio rerio
XP_690770
503
58484
R50
S
H
S
S
S
Q
F
R
Y
Q
S
S
Q
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780697
432
50137
S36
G
S
S
Q
Y
R
L
S
N
N
T
E
I
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
N80
L
K
S
S
G
N
N
N
N
N
N
N
N
G
V
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
S145
S
Q
K
Q
G
S
S
S
S
S
A
A
I
M
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.8
77
99.1
N.A.
68.8
98.9
N.A.
68.8
68.2
68
79.7
N.A.
N.A.
N.A.
N.A.
62.9
Protein Similarity:
100
59.5
79.8
99.5
N.A.
82.9
99.4
N.A.
83
82
81.6
89.2
N.A.
N.A.
N.A.
N.A.
75.8
P-Site Identity:
100
13.3
13.3
100
N.A.
20
100
N.A.
6.6
20
13.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
20
100
N.A.
26.6
100
N.A.
13.3
20
33.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.8
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.1
47.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
24
0
0
8
0
8
24
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
0
0
8
8
0
8
0
0
% D
% Glu:
8
8
0
0
0
0
0
8
0
16
8
8
0
0
16
% E
% Phe:
0
8
0
0
0
0
8
0
0
24
0
0
0
0
8
% F
% Gly:
8
0
0
0
16
8
0
0
0
0
0
0
8
8
0
% G
% His:
0
8
0
0
24
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% I
% Lys:
0
8
8
8
0
0
0
0
8
8
0
0
0
0
0
% K
% Leu:
8
8
16
0
8
8
24
8
16
0
8
8
8
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
8
8
24
16
8
8
8
0
39
% N
% Pro:
39
24
0
8
24
8
8
8
0
0
0
8
8
0
8
% P
% Gln:
8
8
0
16
8
8
0
16
24
8
8
8
31
8
8
% Q
% Arg:
0
24
31
0
0
8
0
8
0
0
24
0
0
0
8
% R
% Ser:
24
8
31
54
8
31
47
47
16
8
16
8
8
54
8
% S
% Thr:
0
0
8
0
0
0
8
0
0
0
8
0
8
0
0
% T
% Val:
8
0
0
8
0
0
0
0
0
8
8
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
8
0
0
24
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _