KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5B
All Species:
16.44
Human Site:
S493
Identified Species:
30.14
UniProt:
Q15173
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15173
NP_006235.1
497
57393
S493
L
T
P
Q
V
A
A
S
G
G
Q
S
_
_
_
Chimpanzee
Pan troglodytes
XP_001151388
673
75031
S589
I
S
K
C
V
S
S
S
H
F
Q
V
A
E
R
Rhesus Macaque
Macaca mulatta
XP_001118226
461
51935
S457
L
T
P
Q
V
A
T
S
G
G
Q
S
_
_
_
Dog
Lupus familis
XP_540876
497
57436
S493
L
T
P
Q
V
A
T
S
G
G
Q
S
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD03
486
56328
A473
A
L
E
K
Q
N
N
A
Y
N
M
H
S
I
R
Rat
Rattus norvegicus
NP_852044
497
57308
S493
P
T
P
Q
V
A
A
S
G
G
Q
S
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506784
467
54655
D462
L
K
R
G
L
R
R
D
G
I
I
P
T
_
_
Chicken
Gallus gallus
XP_419432
476
55266
S463
A
M
A
E
K
Q
N
S
T
H
N
V
L
N
A
Frog
Xenopus laevis
NP_001086500
476
55192
Zebra Danio
Brachydanio rerio
XP_690770
503
58484
S478
L
Q
S
L
T
E
A
S
R
N
Q
K
N
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780697
432
50137
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
V506
K
R
L
E
E
L
G
V
R
K
A
S
_
_
_
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
N736
P
E
L
R
N
S
F
N
T
A
S
E
N
N
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.8
77
99.1
N.A.
68.8
98.9
N.A.
68.8
68.2
68
79.7
N.A.
N.A.
N.A.
N.A.
62.9
Protein Similarity:
100
59.5
79.8
99.5
N.A.
82.9
99.4
N.A.
83
82
81.6
89.2
N.A.
N.A.
N.A.
N.A.
75.8
P-Site Identity:
100
20
91.6
91.6
N.A.
0
91.6
N.A.
15.3
6.6
0
26.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
46.6
91.6
91.6
N.A.
20
91.6
N.A.
23
13.3
0
26.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.8
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.1
47.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
8.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
16.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
0
0
31
24
8
0
8
8
0
8
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
16
8
8
0
0
0
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
39
31
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
8
8
0
0
8
0
% I
% Lys:
8
8
8
8
8
0
0
0
0
8
0
8
0
0
0
% K
% Leu:
39
8
16
8
8
8
0
0
0
0
0
0
8
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
8
8
16
8
0
16
8
0
16
16
0
% N
% Pro:
16
0
31
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
8
0
31
8
8
0
0
0
0
47
0
0
0
8
% Q
% Arg:
0
8
8
8
0
8
8
0
16
0
0
0
0
0
16
% R
% Ser:
0
8
8
0
0
16
8
54
0
0
8
39
8
0
0
% S
% Thr:
0
31
0
0
8
0
16
0
16
0
0
0
8
0
8
% T
% Val:
0
0
0
0
39
0
0
8
0
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
39
47
47
% _