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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP2R5B All Species: 12.73
Human Site: T12 Identified Species: 23.33
UniProt: Q15173 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15173 NP_006235.1 497 57393 T12 L P P A S T P T S P S S P G L
Chimpanzee Pan troglodytes XP_001151388 673 75031 P109 R R E A R S A P A P P C P R L
Rhesus Macaque Macaca mulatta XP_001118226 461 51935 R12 H G G W G Q Q R L P W R L G G
Dog Lupus familis XP_540876 497 57436 T12 L P P A S T P T S P S S P G L
Cat Felis silvestris
Mouse Mus musculus Q6PD03 486 56328 A14 P A P V A C A A I S A S E K V
Rat Rattus norvegicus NP_852044 497 57308 T12 L P P A S T P T S P S S P G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506784 467 54655 D15 P P S V D K V D G F S R K S V
Chicken Gallus gallus XP_419432 476 55266 D12 I S A A E K V D G F T R K S V
Frog Xenopus laevis NP_001086500 476 55192 S17 V D G F T R K S V R K A Q R Q
Zebra Danio Brachydanio rerio XP_690770 503 58484 S14 L P P S S P S S P T T G F S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780697 432 50137
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU89 510 58740 D44 A S T S K S T D N G A A K S H
Baker's Yeast Sacchar. cerevisiae P38903 757 85316 V109 S S S R S S S V S R S G S S S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.8 77 99.1 N.A. 68.8 98.9 N.A. 68.8 68.2 68 79.7 N.A. N.A. N.A. N.A. 62.9
Protein Similarity: 100 59.5 79.8 99.5 N.A. 82.9 99.4 N.A. 83 82 81.6 89.2 N.A. N.A. N.A. N.A. 75.8
P-Site Identity: 100 26.6 13.3 100 N.A. 13.3 100 N.A. 13.3 6.6 0 26.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 40 13.3 100 N.A. 33.3 100 N.A. 20 26.6 26.6 53.3 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 47.8 34.8 N.A.
Protein Similarity: N.A. N.A. N.A. 64.1 47.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 39 8 0 16 8 8 0 16 16 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 8 0 0 8 0 0 24 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 8 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 16 0 0 8 0 0 % F
% Gly: 0 8 16 0 8 0 0 0 16 8 0 16 0 31 8 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 16 8 0 0 0 8 0 24 8 0 % K
% Leu: 31 0 0 0 0 0 0 0 8 0 0 0 8 0 31 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 16 39 39 0 0 8 24 8 8 39 8 0 31 0 0 % P
% Gln: 0 0 0 0 0 8 8 0 0 0 0 0 8 0 8 % Q
% Arg: 8 8 0 8 8 8 0 8 0 16 0 24 0 16 0 % R
% Ser: 8 24 16 16 39 24 16 16 31 8 39 31 8 39 8 % S
% Thr: 0 0 8 0 8 24 8 24 0 8 16 0 0 0 0 % T
% Val: 8 0 0 16 0 0 16 8 8 0 0 0 0 0 31 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _