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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5B
All Species:
25.45
Human Site:
T311
Identified Species:
46.67
UniProt:
Q15173
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15173
NP_006235.1
497
57393
T311
Q
F
L
E
K
D
A
T
L
T
E
H
V
I
R
Chimpanzee
Pan troglodytes
XP_001151388
673
75031
R428
L
F
D
S
E
D
P
R
E
R
D
F
L
K
T
Rhesus Macaque
Macaca mulatta
XP_001118226
461
51935
M298
T
C
T
Q
K
E
V
M
F
L
G
E
M
E
E
Dog
Lupus familis
XP_540876
497
57436
T311
Q
F
L
E
K
D
A
T
L
T
E
H
V
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD03
486
56328
T305
Q
F
L
E
K
D
T
T
L
T
E
P
V
I
R
Rat
Rattus norvegicus
NP_852044
497
57308
T311
Q
F
L
E
K
D
A
T
L
T
E
H
V
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506784
467
54655
S297
Q
F
L
E
K
D
P
S
L
T
E
P
V
I
R
Chicken
Gallus gallus
XP_419432
476
55266
T295
Q
F
L
E
K
D
T
T
L
T
E
P
V
I
R
Frog
Xenopus laevis
NP_001086500
476
55192
A294
Q
F
L
E
K
D
T
A
L
T
E
P
V
I
R
Zebra Danio
Brachydanio rerio
XP_690770
503
58484
T310
Q
F
M
E
K
D
A
T
V
T
E
H
I
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780697
432
50137
K272
L
I
P
L
H
K
V
K
C
L
G
L
Y
H
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
K348
Q
F
V
E
K
D
C
K
L
A
D
T
V
I
R
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
L529
Q
F
L
E
K
D
P
L
L
T
E
E
V
V
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.8
77
99.1
N.A.
68.8
98.9
N.A.
68.8
68.2
68
79.7
N.A.
N.A.
N.A.
N.A.
62.9
Protein Similarity:
100
59.5
79.8
99.5
N.A.
82.9
99.4
N.A.
83
82
81.6
89.2
N.A.
N.A.
N.A.
N.A.
75.8
P-Site Identity:
100
13.3
6.6
100
N.A.
86.6
100
N.A.
80
86.6
80
80
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
33.3
26.6
100
N.A.
86.6
100
N.A.
86.6
86.6
80
100
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.8
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.1
47.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
31
8
0
8
0
0
0
0
8
% A
% Cys:
0
8
0
0
0
0
8
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
85
0
0
0
0
16
0
0
0
0
% D
% Glu:
0
0
0
77
8
8
0
0
8
0
70
16
0
8
8
% E
% Phe:
0
85
0
0
0
0
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
31
0
8
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
8
70
0
% I
% Lys:
0
0
0
0
85
8
0
16
0
0
0
0
0
8
0
% K
% Leu:
16
0
62
8
0
0
0
8
70
16
0
8
8
0
0
% L
% Met:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
24
0
0
0
0
31
0
0
0
% P
% Gln:
77
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
70
% R
% Ser:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% S
% Thr:
8
0
8
0
0
0
24
47
0
70
0
8
0
0
8
% T
% Val:
0
0
8
0
0
0
16
0
8
0
0
0
70
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _