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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5B
All Species:
40
Human Site:
Y221
Identified Species:
73.33
UniProt:
Q15173
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15173
NP_006235.1
497
57393
Y221
K
T
I
L
H
R
V
Y
G
K
F
L
G
L
R
Chimpanzee
Pan troglodytes
XP_001151388
673
75031
V331
R
A
T
L
N
E
L
V
E
Y
V
S
T
N
R
Rhesus Macaque
Macaca mulatta
XP_001118226
461
51935
S197
G
P
T
L
L
A
L
S
P
P
A
F
L
F
C
Dog
Lupus familis
XP_540876
497
57436
Y221
K
T
I
L
H
R
V
Y
G
K
F
L
G
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD03
486
56328
Y215
K
T
V
L
H
R
I
Y
G
K
F
L
G
L
R
Rat
Rattus norvegicus
NP_852044
497
57308
Y221
K
T
I
L
H
R
V
Y
G
K
F
L
G
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506784
467
54655
Y207
K
T
V
L
H
R
I
Y
G
K
F
L
G
L
R
Chicken
Gallus gallus
XP_419432
476
55266
Y205
K
T
V
L
H
R
I
Y
G
K
F
L
G
L
R
Frog
Xenopus laevis
NP_001086500
476
55192
Y204
K
T
V
L
H
R
I
Y
G
K
F
L
G
L
R
Zebra Danio
Brachydanio rerio
XP_690770
503
58484
Y220
K
T
I
L
H
R
V
Y
G
K
L
L
G
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780697
432
50137
L184
F
V
M
H
L
L
E
L
F
D
S
E
D
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
Y258
K
T
I
L
H
R
I
Y
G
K
F
M
V
H
R
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
Y439
K
T
T
L
H
R
I
Y
G
K
F
L
S
L
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.8
77
99.1
N.A.
68.8
98.9
N.A.
68.8
68.2
68
79.7
N.A.
N.A.
N.A.
N.A.
62.9
Protein Similarity:
100
59.5
79.8
99.5
N.A.
82.9
99.4
N.A.
83
82
81.6
89.2
N.A.
N.A.
N.A.
N.A.
75.8
P-Site Identity:
100
13.3
6.6
100
N.A.
86.6
100
N.A.
86.6
86.6
86.6
93.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
13.3
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.8
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.1
47.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
80
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
8
8
0
8
0
0
8
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
8
0
70
8
0
8
0
% F
% Gly:
8
0
0
0
0
0
0
0
77
0
0
0
62
0
0
% G
% His:
0
0
0
8
77
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
39
0
0
0
47
0
0
0
0
0
0
0
0
% I
% Lys:
77
0
0
0
0
0
0
0
0
77
0
0
0
0
0
% K
% Leu:
0
0
0
93
16
8
16
8
0
0
8
70
8
70
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
8
8
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
77
0
0
0
0
0
0
0
0
93
% R
% Ser:
0
0
0
0
0
0
0
8
0
0
8
8
8
0
0
% S
% Thr:
0
77
24
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
8
31
0
0
0
31
8
0
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _