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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5B
All Species:
33.94
Human Site:
Y406
Identified Species:
62.22
UniProt:
Q15173
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15173
NP_006235.1
497
57393
Y406
P
A
V
F
G
T
L
Y
Q
V
S
K
E
H
W
Chimpanzee
Pan troglodytes
XP_001151388
673
75031
L518
L
A
L
F
H
A
Q
L
A
Y
C
V
V
Q
F
Rhesus Macaque
Macaca mulatta
XP_001118226
461
51935
Y386
Q
T
I
V
S
L
I
Y
N
V
L
K
T
F
M
Dog
Lupus familis
XP_540876
497
57436
Y406
P
A
V
F
G
T
L
Y
Q
V
S
K
E
H
W
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD03
486
56328
Y400
P
I
M
F
A
S
L
Y
K
I
S
K
E
H
W
Rat
Rattus norvegicus
NP_852044
497
57308
Y406
P
A
V
F
G
T
L
Y
Q
V
S
K
E
H
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506784
467
54655
Y392
P
I
M
F
S
S
L
Y
R
I
S
K
E
H
W
Chicken
Gallus gallus
XP_419432
476
55266
Y390
P
I
M
F
G
S
L
Y
K
I
S
K
E
H
W
Frog
Xenopus laevis
NP_001086500
476
55192
Y389
P
I
M
F
G
S
L
Y
K
I
S
K
E
H
W
Zebra Danio
Brachydanio rerio
XP_690770
503
58484
Y405
P
L
V
F
G
T
L
Y
R
V
S
K
E
H
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780697
432
50137
R359
P
H
F
Q
V
A
E
R
A
L
Y
F
W
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
L435
M
Q
N
R
K
V
I
L
P
I
I
F
P
A
L
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
Y624
P
I
I
F
P
A
L
Y
E
L
T
S
Q
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.8
77
99.1
N.A.
68.8
98.9
N.A.
68.8
68.2
68
79.7
N.A.
N.A.
N.A.
N.A.
62.9
Protein Similarity:
100
59.5
79.8
99.5
N.A.
82.9
99.4
N.A.
83
82
81.6
89.2
N.A.
N.A.
N.A.
N.A.
75.8
P-Site Identity:
100
13.3
20
100
N.A.
60
100
N.A.
60
66.6
66.6
86.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
33.3
100
N.A.
86.6
100
N.A.
86.6
93.3
93.3
93.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.8
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.1
47.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
0
0
8
24
0
0
16
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
8
0
0
0
62
0
8
% E
% Phe:
0
0
8
77
0
0
0
0
0
0
0
16
0
8
8
% F
% Gly:
0
0
0
0
47
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
8
0
0
0
0
0
0
0
0
62
0
% H
% Ile:
0
39
16
0
0
0
16
0
0
39
8
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
24
0
0
70
0
0
0
% K
% Leu:
8
8
8
0
0
8
70
16
0
16
8
0
0
8
8
% L
% Met:
8
0
31
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
8
0
0
0
0
8
8
% N
% Pro:
77
0
0
0
8
0
0
0
8
0
0
0
8
0
0
% P
% Gln:
8
8
0
8
0
0
8
0
24
0
0
0
8
8
0
% Q
% Arg:
0
0
0
8
0
0
0
8
16
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
16
31
0
0
0
0
62
8
0
0
0
% S
% Thr:
0
8
0
0
0
31
0
0
0
0
8
0
8
0
0
% T
% Val:
0
0
31
8
8
8
0
0
0
39
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
62
% W
% Tyr:
0
0
0
0
0
0
0
77
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _