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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPA1 All Species: 26.64
Human Site: S5 Identified Species: 39.07
UniProt: Q15181 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15181 NP_066952.1 289 32660 S5 _ _ _ M S G F S T E E R A A P
Chimpanzee Pan troglodytes XP_001164495 327 36742 S43 S G T M N G F S T E E R A A P
Rhesus Macaque Macaca mulatta XP_001107614 488 53839 S204 S G T M S G F S T E E R A A P
Dog Lupus familis XP_536380 290 32918 S6 _ _ M E L E T S E R G A R R A
Cat Felis silvestris
Mouse Mus musculus Q9D819 289 32649 S5 _ _ _ M S G F S S E E R A A P
Rat Rattus norvegicus NP_001094304 289 32753 S5 _ _ _ M S S F S S E E R A A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232700 290 32618 S5 _ _ _ M A G Y S V E E R A A P
Frog Xenopus laevis NP_001086030 289 32999 E6 _ _ M S Y S V E Q R A K A N S
Zebra Danio Brachydanio rerio NP_001017833 291 32624 E6 _ _ M S F L T E E R G N P N T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O77460 338 37921 E53 S H E M A L Y E T V E K G A K
Honey Bee Apis mellifera XP_393267 745 83891 T48 Y A K K M S Y T T I E R G A L
Nematode Worm Caenorhab. elegans Q18680 407 44134 E127 A G D S A V Y E A V E R G S L
Sea Urchin Strong. purpuratus XP_793193 270 30364 F10 N V Q V I S P F H D I P L Y A
Poplar Tree Populus trichocarpa
Maize Zea mays O48556 214 24351
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P00817 287 32281 T5 _ _ _ M T Y T T R Q I G A K N
Red Bread Mold Neurospora crassa Q6MVH7 290 32621 Y5 _ _ _ M A S Q Y S V R K V G A
Conservation
Percent
Protein Identity: 100 88 59 93 N.A. 94.1 92.3 N.A. N.A. 77.5 72.3 72.8 N.A. 47.9 23 38.8 53.9
Protein Similarity: 100 88.3 59.2 95.8 N.A. 98.9 98.6 N.A. N.A. 90.6 84.7 85.5 N.A. 60.3 29.9 53.8 68.5
P-Site Identity: 100 73.3 80 7.6 N.A. 91.6 83.3 N.A. N.A. 75 7.6 0 N.A. 26.6 26.6 13.3 0
P-Site Similarity: 100 86.6 86.6 7.6 N.A. 100 91.6 N.A. N.A. 91.6 15.3 0 N.A. 46.6 46.6 40 13.3
Percent
Protein Identity: N.A. 21.1 N.A. N.A. 52.6 49.3
Protein Similarity: N.A. 38 N.A. N.A. 70.2 68.6
P-Site Identity: N.A. 0 N.A. N.A. 16.6 8.3
P-Site Similarity: N.A. 0 N.A. N.A. 41.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 25 0 0 0 7 0 7 7 50 50 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % D
% Glu: 0 0 7 7 0 7 0 25 13 38 57 0 0 0 0 % E
% Phe: 0 0 0 0 7 0 32 7 0 0 0 0 0 0 0 % F
% Gly: 0 19 0 0 0 32 0 0 0 0 13 7 19 7 0 % G
% His: 0 7 0 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 0 0 0 7 13 0 0 0 0 % I
% Lys: 0 0 7 7 0 0 0 0 0 0 0 19 0 7 7 % K
% Leu: 0 0 0 0 7 13 0 0 0 0 0 0 7 0 13 % L
% Met: 0 0 19 57 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 7 0 0 0 0 0 0 7 0 13 7 % N
% Pro: 0 0 0 0 0 0 7 0 0 0 0 7 7 0 38 % P
% Gln: 0 0 7 0 0 0 7 0 7 7 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 7 19 7 50 7 7 0 % R
% Ser: 19 0 0 19 25 32 0 44 19 0 0 0 0 7 7 % S
% Thr: 0 0 13 0 7 0 19 13 32 0 0 0 0 0 7 % T
% Val: 0 7 0 7 0 7 7 0 7 19 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 7 7 25 7 0 0 0 0 0 7 0 % Y
% Spaces: 57 57 38 0 0 0 0 0 0 0 0 0 0 0 0 % _