Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPA1 All Species: 35.76
Human Site: Y80 Identified Species: 52.44
UniProt: Q15181 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15181 NP_066952.1 289 32660 Y80 V K K G K L R Y V A N L F P Y
Chimpanzee Pan troglodytes XP_001164495 327 36742 Y118 V K K G K L R Y V A N L F P Y
Rhesus Macaque Macaca mulatta XP_001107614 488 53839 Y279 V K K G K L R Y V A N L F P Y
Dog Lupus familis XP_536380 290 32918 Y81 V K K G K L R Y V A N L F P Y
Cat Felis silvestris
Mouse Mus musculus Q9D819 289 32649 Y80 V K K G K L R Y V A N L F P Y
Rat Rattus norvegicus NP_001094304 289 32753 Y80 V K K G K L R Y V A N L F P Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232700 290 32618 Y82 V K K G K L R Y V A N V F P H
Frog Xenopus laevis NP_001086030 289 32999 F81 V K K G K L R F V A N V F P H
Zebra Danio Brachydanio rerio NP_001017833 291 32624 Y81 V K K G N L R Y V A N V F P H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O77460 338 37921 F130 I K K G K L R F V A N C F P H
Honey Bee Apis mellifera XP_393267 745 83891 Y124 V K K G K L R Y V A N C F P H
Nematode Worm Caenorhab. elegans Q18680 407 44134 F203 E K K G V A R F V H N I F P H
Sea Urchin Strong. purpuratus XP_793193 270 30364 N85 P Q T W E D P N H T D A S T K
Poplar Tree Populus trichocarpa
Maize Zea mays O48556 214 24351 I43 H P W H D L E I G P D A P A V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P00817 287 32281 F80 T K K G K L R F V R N C F P H
Red Bread Mold Neurospora crassa Q6MVH7 290 32621 F82 T K K G K L R F V R N C F P H
Conservation
Percent
Protein Identity: 100 88 59 93 N.A. 94.1 92.3 N.A. N.A. 77.5 72.3 72.8 N.A. 47.9 23 38.8 53.9
Protein Similarity: 100 88.3 59.2 95.8 N.A. 98.9 98.6 N.A. N.A. 90.6 84.7 85.5 N.A. 60.3 29.9 53.8 68.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 86.6 80 80 N.A. 73.3 86.6 53.3 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 93.3 N.A. 93.3 93.3 73.3 20
Percent
Protein Identity: N.A. 21.1 N.A. N.A. 52.6 49.3
Protein Similarity: N.A. 38 N.A. N.A. 70.2 68.6
P-Site Identity: N.A. 6.6 N.A. N.A. 66.6 66.6
P-Site Similarity: N.A. 13.3 N.A. N.A. 80 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 0 0 69 0 13 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 % C
% Asp: 0 0 0 0 7 7 0 0 0 0 13 0 0 0 0 % D
% Glu: 7 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 32 0 0 0 0 88 0 0 % F
% Gly: 0 0 0 88 0 0 0 0 7 0 0 0 0 0 0 % G
% His: 7 0 0 7 0 0 0 0 7 7 0 0 0 0 50 % H
% Ile: 7 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % I
% Lys: 0 88 88 0 75 0 0 0 0 0 0 0 0 0 7 % K
% Leu: 0 0 0 0 0 88 0 0 0 0 0 38 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 7 0 0 88 0 0 0 0 % N
% Pro: 7 7 0 0 0 0 7 0 0 7 0 0 7 88 0 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 88 0 0 13 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % S
% Thr: 13 0 7 0 0 0 0 0 0 7 0 0 0 7 0 % T
% Val: 63 0 0 0 7 0 0 0 88 0 0 19 0 0 7 % V
% Trp: 0 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 57 0 0 0 0 0 0 38 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _