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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTGES3
All Species:
22.73
Human Site:
S124
Identified Species:
41.67
UniProt:
Q15185
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15185
NP_006592.3
160
18697
S124
M
S
N
F
D
R
F
S
E
M
M
N
N
M
G
Chimpanzee
Pan troglodytes
XP_001159085
160
18695
S124
M
S
N
F
D
R
F
S
E
M
M
N
N
M
G
Rhesus Macaque
Macaca mulatta
XP_001115374
139
16458
D114
K
D
W
E
D
D
S
D
E
D
M
S
N
F
D
Dog
Lupus familis
XP_848910
500
54559
S464
M
S
N
F
D
R
F
S
E
M
M
N
N
M
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0Q7
160
18703
S124
M
S
N
F
D
R
F
S
E
M
M
D
H
M
G
Rat
Rattus norvegicus
NP_001014294
149
17334
G121
E
M
M
D
H
M
G
G
D
E
D
A
D
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512870
235
26525
S196
L
S
N
F
D
R
F
S
E
M
M
N
N
M
G
Chicken
Gallus gallus
Q90955
146
16851
D119
M
M
N
N
M
G
G
D
D
D
V
D
L
P
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998335
159
18446
S124
L
S
S
F
D
R
F
S
E
M
M
N
N
M
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VH95
184
20734
G130
Q
K
D
N
S
M
F
G
N
F
L
N
S
P
G
Honey Bee
Apis mellifera
XP_624846
176
20104
D130
G
M
E
G
S
S
H
D
L
E
E
M
M
R
Q
Nematode Worm
Caenorhab. elegans
Q23280
175
19413
G123
D
A
G
A
G
I
G
G
G
M
A
N
G
F
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P28707
216
24063
Q142
A
E
G
N
D
A
A
Q
G
M
D
F
S
Q
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
86.8
32
N.A.
98.7
81.8
N.A.
63.4
87.5
N.A.
79.3
N.A.
23.3
36.9
27.4
N.A.
Protein Similarity:
100
100
86.8
32
N.A.
100
85.6
N.A.
65.1
90
N.A.
90.6
N.A.
41.2
51.1
47.4
N.A.
P-Site Identity:
100
100
26.6
100
N.A.
86.6
0
N.A.
93.3
13.3
N.A.
86.6
N.A.
20
0
13.3
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
100
20
N.A.
100
33.3
N.A.
100
N.A.
40
0
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
8
8
0
0
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
8
62
8
0
24
16
16
16
16
8
0
16
% D
% Glu:
8
8
8
8
0
0
0
0
54
16
8
0
0
0
8
% E
% Phe:
0
0
0
47
0
0
54
0
0
8
0
8
0
16
0
% F
% Gly:
8
0
16
8
8
8
24
24
16
0
0
0
8
0
54
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
16
0
0
0
0
0
0
0
8
0
8
0
8
8
0
% L
% Met:
39
24
8
0
8
16
0
0
0
62
54
8
8
47
8
% M
% Asn:
0
0
47
24
0
0
0
0
8
0
0
54
47
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
8
% P
% Gln:
8
0
0
0
0
0
0
8
0
0
0
0
0
8
8
% Q
% Arg:
0
0
0
0
0
47
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
47
8
0
16
8
8
47
0
0
0
8
16
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _