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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTGES3 All Species: 21.82
Human Site: S82 Identified Species: 40
UniProt: Q15185 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15185 NP_006592.3 160 18697 S82 C C L R K G E S G Q S W P R L
Chimpanzee Pan troglodytes XP_001159085 160 18695 S82 C C L R K G E S G Q S W P R L
Rhesus Macaque Macaca mulatta XP_001115374 139 16458 S72 K H K R T D R S I L C C L R K
Dog Lupus familis XP_848910 500 54559 S422 C C L R K G E S G Q S W P R L
Cat Felis silvestris
Mouse Mus musculus Q9R0Q7 160 18703 S82 C C L R K G E S G Q S W P R L
Rat Rattus norvegicus NP_001014294 149 17334 T79 D H S W P R L T K E R A K L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512870 235 26525 S154 C C L R K G E S G Q S W P R L
Chicken Gallus gallus Q90955 146 16851 K77 Q A W P R L T K E R A K L N W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998335 159 18446 P82 C C L K K A E P G K S W P R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VH95 184 20734 A88 F T I P K K A A G P Y W S S L
Honey Bee Apis mellifera XP_624846 176 20104 E88 L V L F K K E E G P Y W P R L
Nematode Worm Caenorhab. elegans Q23280 175 19413 T81 E I T V Q K K T P A W W P R L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P28707 216 24063 E100 K L Y K K D L E S E Y W P R L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 86.8 32 N.A. 98.7 81.8 N.A. 63.4 87.5 N.A. 79.3 N.A. 23.3 36.9 27.4 N.A.
Protein Similarity: 100 100 86.8 32 N.A. 100 85.6 N.A. 65.1 90 N.A. 90.6 N.A. 41.2 51.1 47.4 N.A.
P-Site Identity: 100 100 20 100 N.A. 100 0 N.A. 100 0 N.A. 73.3 N.A. 26.6 53.3 26.6 N.A.
P-Site Similarity: 100 100 20 100 N.A. 100 13.3 N.A. 100 20 N.A. 86.6 N.A. 40 53.3 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 8 8 8 0 8 8 8 0 0 0 % A
% Cys: 47 47 0 0 0 0 0 0 0 0 8 8 0 0 0 % C
% Asp: 8 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 54 16 8 16 0 0 0 0 0 % E
% Phe: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 39 0 0 62 0 0 0 0 0 0 % G
% His: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 16 0 8 16 70 24 8 8 8 8 0 8 8 0 8 % K
% Leu: 8 8 54 0 0 8 16 0 0 8 0 0 16 8 77 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % N
% Pro: 0 0 0 16 8 0 0 8 8 16 0 0 70 0 0 % P
% Gln: 8 0 0 0 8 0 0 0 0 39 0 0 0 0 0 % Q
% Arg: 0 0 0 47 8 8 8 0 0 8 8 0 0 77 0 % R
% Ser: 0 0 8 0 0 0 0 47 8 0 47 0 8 8 0 % S
% Thr: 0 8 8 0 8 0 8 16 0 0 0 0 0 0 0 % T
% Val: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 8 8 0 0 0 0 0 0 8 77 0 0 8 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 24 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _