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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTGES3
All Species:
19.7
Human Site:
Y14
Identified Species:
36.11
UniProt:
Q15185
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15185
NP_006592.3
160
18697
Y14
K
W
Y
D
R
R
D
Y
V
F
I
E
F
C
V
Chimpanzee
Pan troglodytes
XP_001159085
160
18695
Y14
K
W
Y
D
R
R
D
Y
V
F
I
E
F
C
V
Rhesus Macaque
Macaca mulatta
XP_001115374
139
16458
Y9
Q
P
A
S
A
K
W
Y
D
R
R
D
Y
V
F
Dog
Lupus familis
XP_848910
500
54559
Y354
K
W
Y
D
R
R
D
Y
V
F
I
E
F
C
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0Q7
160
18703
Y14
K
W
Y
D
R
R
D
Y
V
F
I
E
F
C
V
Rat
Rattus norvegicus
NP_001014294
149
17334
D15
F
C
G
L
D
S
K
D
V
N
V
N
F
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512870
235
26525
Y86
K
W
Y
D
R
R
D
Y
V
F
I
E
F
C
V
Chicken
Gallus gallus
Q90955
146
16851
N14
V
E
D
S
K
D
V
N
V
N
F
E
K
S
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998335
159
18446
A14
K
W
Y
D
R
R
E
A
V
F
I
E
F
C
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VH95
184
20734
L20
S
W
A
Q
R
N
D
L
I
Y
V
I
I
D
V
Honey Bee
Apis mellifera
XP_624846
176
20104
I20
M
W
A
Q
R
K
D
I
L
F
V
T
I
C
L
Nematode Worm
Caenorhab. elegans
Q23280
175
19413
L15
L
W
A
Q
R
E
S
L
V
Y
L
T
I
E
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P28707
216
24063
L27
D
P
E
R
N
Y
V
L
I
T
V
S
I
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
86.8
32
N.A.
98.7
81.8
N.A.
63.4
87.5
N.A.
79.3
N.A.
23.3
36.9
27.4
N.A.
Protein Similarity:
100
100
86.8
32
N.A.
100
85.6
N.A.
65.1
90
N.A.
90.6
N.A.
41.2
51.1
47.4
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
13.3
N.A.
100
13.3
N.A.
80
N.A.
26.6
33.3
26.6
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
100
20
N.A.
100
20
N.A.
93.3
N.A.
46.6
60
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
31
0
8
0
0
8
0
0
0
0
0
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
54
0
% C
% Asp:
8
0
8
47
8
8
54
8
8
0
0
8
0
8
8
% D
% Glu:
0
8
8
0
0
8
8
0
0
0
0
54
0
16
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
54
8
0
54
0
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
16
0
47
8
31
0
8
% I
% Lys:
47
0
0
0
8
16
8
0
0
0
0
0
8
0
16
% K
% Leu:
8
0
0
8
0
0
0
24
8
0
8
0
0
0
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
8
0
16
0
8
0
0
0
% N
% Pro:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
70
47
0
0
0
8
8
0
0
0
0
% R
% Ser:
8
0
0
16
0
8
8
0
0
0
0
8
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
16
0
0
0
% T
% Val:
8
0
0
0
0
0
16
0
70
0
31
0
0
8
54
% V
% Trp:
0
70
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
47
0
0
8
0
47
0
16
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _