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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PVRL1
All Species:
23.03
Human Site:
Y418
Identified Species:
56.3
UniProt:
Q15223
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15223
NP_002846.3
517
57158
Y418
P
M
A
Q
N
L
Q
Y
P
D
D
S
D
D
E
Chimpanzee
Pan troglodytes
XP_001150719
368
40524
L279
A
V
L
T
V
F
F
L
Y
N
R
Q
Q
K
S
Rhesus Macaque
Macaca mulatta
XP_001098654
785
85572
Y687
P
M
A
Q
N
L
Q
Y
P
D
D
S
D
D
E
Dog
Lupus familis
XP_546481
516
56940
Y418
P
M
A
Q
N
L
Q
Y
P
D
D
S
D
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKF6
515
57046
Y417
P
M
A
Q
N
L
Q
Y
P
D
D
S
D
D
E
Rat
Rattus norvegicus
XP_236210
515
57138
Y417
P
M
A
Q
N
L
Q
Y
P
D
D
S
D
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506347
506
55450
Y403
P
A
A
Q
N
L
Q
Y
P
E
D
S
D
D
D
Chicken
Gallus gallus
XP_417892
987
111054
L882
E
D
I
Q
V
V
H
L
D
N
M
T
H
E
E
Frog
Xenopus laevis
NP_001087644
463
50753
T374
G
K
P
S
Q
E
F
T
Y
Q
D
D
S
E
M
Zebra Danio
Brachydanio rerio
Q58EG3
574
63977
R469
T
I
Y
P
D
K
D
R
E
E
W
G
D
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.6
64.9
97
N.A.
94.1
94.7
N.A.
76.2
28.8
32.6
29.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
58.6
65.6
98.6
N.A.
97.6
98.2
N.A.
84.9
34.7
48.3
44.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
80
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
93.3
40
13.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
60
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
0
10
0
10
50
70
10
70
60
20
% D
% Glu:
10
0
0
0
0
10
0
0
10
20
0
0
0
20
60
% E
% Phe:
0
0
0
0
0
10
20
0
0
0
0
0
0
10
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
10
0
0
60
0
20
0
0
0
0
0
0
0
% L
% Met:
0
50
0
0
0
0
0
0
0
0
10
0
0
0
10
% M
% Asn:
0
0
0
0
60
0
0
0
0
20
0
0
0
0
0
% N
% Pro:
60
0
10
10
0
0
0
0
60
0
0
0
0
0
0
% P
% Gln:
0
0
0
70
10
0
60
0
0
10
0
10
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
0
0
0
0
60
10
0
10
% S
% Thr:
10
0
0
10
0
0
0
10
0
0
0
10
0
0
0
% T
% Val:
0
10
0
0
20
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
60
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _