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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R4
All Species:
5.45
Human Site:
S12
Identified Species:
9.23
UniProt:
Q15257
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15257
NP_066954.2
358
40668
S12
E
R
Q
P
P
P
D
S
S
E
E
A
P
P
A
Chimpanzee
Pan troglodytes
XP_001163459
373
41748
G10
S
H
L
L
E
P
A
G
A
H
L
S
S
G
S
Rhesus Macaque
Macaca mulatta
XP_001108890
359
40767
S12
E
R
Q
P
P
P
D
S
S
E
E
A
P
P
A
Dog
Lupus familis
XP_548424
349
39477
A9
A
A
A
S
H
P
P
A
G
R
W
L
L
G
R
Cat
Felis silvestris
Mouse
Mus musculus
P58389
323
36692
P9
A
E
G
E
R
Q
P
P
P
D
S
S
E
E
T
Rat
Rattus norvegicus
NP_001102047
323
36599
P9
A
E
G
E
R
Q
P
P
P
D
S
S
E
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508723
358
40562
I14
H
P
A
E
K
D
E
I
W
A
G
N
A
A
K
Chicken
Gallus gallus
NP_001026542
321
36721
A8
M
A
E
S
E
R
R
A
G
N
S
E
E
M
A
Frog
Xenopus laevis
NP_001089500
323
36857
T8
M
A
E
K
E
Q
N
T
D
H
A
E
D
E
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523466
398
44238
A14
Q
A
A
G
K
L
P
A
I
A
K
K
V
Q
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784258
466
51558
A71
D
F
I
P
G
E
K
A
G
I
F
D
S
D
M
Poplar Tree
Populus trichocarpa
XP_002307365
396
45132
N10
E
P
Q
E
H
N
H
N
H
Q
D
P
P
K
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40454
393
45064
A11
D
R
V
D
W
P
H
A
T
F
S
T
P
V
K
Red Bread Mold
Neurospora crassa
Q7SEF9
449
50080
A21
T
G
Q
G
S
P
A
A
S
G
Q
P
I
S
K
Conservation
Percent
Protein Identity:
100
72.1
93.3
73.4
N.A.
86.8
85.7
N.A.
68.7
81.2
76.2
N.A.
N.A.
41.2
N.A.
N.A.
39
Protein Similarity:
100
76.9
96
77.3
N.A.
89.6
89.1
N.A.
75.9
85.1
82.6
N.A.
N.A.
56
N.A.
N.A.
50.4
P-Site Identity:
100
6.6
100
6.6
N.A.
0
0
N.A.
0
6.6
0
N.A.
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
100
13.3
N.A.
13.3
13.3
N.A.
6.6
20
20
N.A.
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
38.3
N.A.
N.A.
N.A.
36.1
30.2
Protein Similarity:
56.8
N.A.
N.A.
N.A.
50.3
43.8
P-Site Identity:
20
N.A.
N.A.
N.A.
20
20
P-Site Similarity:
46.6
N.A.
N.A.
N.A.
40
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
29
22
0
0
0
15
43
8
15
8
15
8
8
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
8
0
8
15
0
8
15
8
8
8
8
0
% D
% Glu:
22
15
15
29
22
8
8
0
0
15
15
15
22
22
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
8
15
15
8
0
0
8
22
8
8
0
0
15
0
% G
% His:
8
8
0
0
15
0
15
0
8
15
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
8
8
0
0
8
0
8
% I
% Lys:
0
0
0
8
15
0
8
0
0
0
8
8
0
8
22
% K
% Leu:
0
0
8
8
0
8
0
0
0
0
8
8
8
0
0
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
0
0
0
8
8
8
0
8
0
8
0
0
8
% N
% Pro:
0
15
0
22
15
43
29
15
15
0
0
15
29
15
0
% P
% Gln:
8
0
29
0
0
22
0
0
0
8
8
0
0
8
0
% Q
% Arg:
0
22
0
0
15
8
8
0
0
8
0
0
0
0
8
% R
% Ser:
8
0
0
15
8
0
0
15
22
0
29
22
15
8
15
% S
% Thr:
8
0
0
0
0
0
0
8
8
0
0
8
0
0
15
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
8
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _