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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX1-1
All Species:
2.42
Human Site:
S146
Identified Species:
4.85
UniProt:
Q15270
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15270
XP_931434.4
411
40659
S146
G
G
G
G
H
S
P
S
A
D
S
G
D
E
V
Chimpanzee
Pan troglodytes
XP_001174299
590
60761
L139
C
E
R
L
N
L
A
L
S
F
S
L
T
E
T
Rhesus Macaque
Macaca mulatta
XP_001082431
415
41783
P159
E
P
P
N
A
G
D
P
Y
K
A
G
E
A
E
Dog
Lupus familis
XP_544059
354
36219
G101
A
G
K
D
A
S
P
G
D
S
A
R
Q
R
E
Cat
Felis silvestris
Mouse
Mus musculus
P42580
305
31994
G56
S
L
E
E
V
E
A
G
Q
D
A
C
S
G
N
Rat
Rattus norvegicus
P63156
327
35117
L78
G
P
G
L
D
S
H
L
Q
P
G
Q
L
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514461
324
33600
N75
I
L
D
P
N
K
F
N
S
K
K
L
L
L
Y
Chicken
Gallus gallus
P19601
232
25205
Frog
Xenopus laevis
Q91907
340
37176
C91
P
S
L
P
G
G
F
C
S
S
L
A
Q
G
M
Zebra Danio
Brachydanio rerio
P22574
246
27686
Tiger Blowfish
Takifugu rubipres
O13074
288
32704
S39
H
S
P
D
Y
Y
S
S
Q
R
Q
E
P
A
A
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001009577
432
47583
S155
G
R
D
S
E
C
L
S
S
P
N
D
D
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.3
85
38.9
N.A.
42.3
26
N.A.
30.1
20.1
22.8
20.6
21.1
N.A.
N.A.
N.A.
28.9
Protein Similarity:
100
29.6
86.9
47.2
N.A.
49.8
35.2
N.A.
35.5
25
33.5
31.3
32.6
N.A.
N.A.
N.A.
38.1
P-Site Identity:
100
13.3
6.6
20
N.A.
6.6
20
N.A.
0
0
0
0
6.6
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
26.6
20
26.6
N.A.
13.3
20
N.A.
20
0
13.3
0
13.3
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
17
0
17
0
9
0
25
9
0
17
17
% A
% Cys:
9
0
0
0
0
9
0
9
0
0
0
9
0
0
0
% C
% Asp:
0
0
17
17
9
0
9
0
9
17
0
9
17
0
9
% D
% Glu:
9
9
9
9
9
9
0
0
0
0
0
9
9
17
17
% E
% Phe:
0
0
0
0
0
0
17
0
0
9
0
0
0
0
0
% F
% Gly:
25
17
17
9
9
17
0
17
0
0
9
17
0
17
0
% G
% His:
9
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
9
0
0
0
17
9
0
0
0
0
% K
% Leu:
0
17
9
17
0
9
9
17
0
0
9
17
17
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
9
17
0
0
9
0
0
9
0
0
0
9
% N
% Pro:
9
17
17
17
0
0
17
9
0
17
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
25
0
9
9
17
9
0
% Q
% Arg:
0
9
9
0
0
0
0
0
0
9
0
9
0
9
0
% R
% Ser:
9
17
0
9
0
25
9
25
34
17
17
0
9
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% T
% Val:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
9
0
0
9
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _