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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX1-1
All Species:
6.06
Human Site:
S351
Identified Species:
12.12
UniProt:
Q15270
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15270
XP_931434.4
411
40659
S351
P
G
G
L
S
P
L
S
P
S
P
P
M
G
A
Chimpanzee
Pan troglodytes
XP_001174299
590
60761
L451
R
R
A
Q
T
E
A
L
A
I
T
R
A
L
G
Rhesus Macaque
Macaca mulatta
XP_001082431
415
41783
S355
P
G
G
L
S
P
L
S
P
S
P
P
M
G
A
Dog
Lupus familis
XP_544059
354
36219
G294
G
G
G
G
G
G
A
G
G
S
P
G
A
P
G
Cat
Felis silvestris
Mouse
Mus musculus
P42580
305
31994
P249
G
S
A
T
G
S
S
P
G
P
P
V
P
G
A
Rat
Rattus norvegicus
P63156
327
35117
L271
P
Q
S
L
V
S
N
L
D
P
G
A
A
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514461
324
33600
F268
L
V
A
L
E
N
K
F
K
S
T
R
Y
L
S
Chicken
Gallus gallus
P19601
232
25205
R176
A
S
P
F
P
P
G
R
P
R
R
R
T
L
R
Frog
Xenopus laevis
Q91907
340
37176
K284
K
L
S
E
V
Q
V
K
I
W
F
Q
N
R
R
Zebra Danio
Brachydanio rerio
P22574
246
27686
C189
V
E
I
A
H
T
L
C
L
S
E
R
Q
I
K
Tiger Blowfish
Takifugu rubipres
O13074
288
32704
N232
K
V
R
S
G
S
T
N
T
N
S
Q
V
L
T
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001009577
432
47583
T367
A
P
T
T
T
S
V
T
A
T
H
P
S
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.3
85
38.9
N.A.
42.3
26
N.A.
30.1
20.1
22.8
20.6
21.1
N.A.
N.A.
N.A.
28.9
Protein Similarity:
100
29.6
86.9
47.2
N.A.
49.8
35.2
N.A.
35.5
25
33.5
31.3
32.6
N.A.
N.A.
N.A.
38.1
P-Site Identity:
100
0
100
26.6
N.A.
20
13.3
N.A.
13.3
13.3
0
13.3
0
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
100
26.6
N.A.
20
13.3
N.A.
20
13.3
6.6
13.3
20
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
25
9
0
0
17
0
17
0
0
9
25
0
25
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
9
0
9
9
9
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
9
0
0
9
0
0
0
0
% F
% Gly:
17
25
25
9
25
9
9
9
17
0
9
9
0
25
17
% G
% His:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
9
9
0
0
0
9
0
% I
% Lys:
17
0
0
0
0
0
9
9
9
0
0
0
0
0
9
% K
% Leu:
9
9
0
34
0
0
25
17
9
0
0
0
0
42
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% M
% Asn:
0
0
0
0
0
9
9
9
0
9
0
0
9
0
0
% N
% Pro:
25
9
9
0
9
25
0
9
25
17
34
25
9
17
9
% P
% Gln:
0
9
0
9
0
9
0
0
0
0
0
17
9
0
0
% Q
% Arg:
9
9
9
0
0
0
0
9
0
9
9
34
0
9
17
% R
% Ser:
0
17
17
9
17
34
9
17
0
42
9
0
9
0
9
% S
% Thr:
0
0
9
17
17
9
9
9
9
9
17
0
9
0
9
% T
% Val:
9
17
0
0
17
0
17
0
0
0
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _