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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX1-1
All Species:
5.15
Human Site:
S58
Identified Species:
10.3
UniProt:
Q15270
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15270
XP_931434.4
411
40659
S58
L
D
P
N
K
F
N
S
R
R
R
R
C
V
L
Chimpanzee
Pan troglodytes
XP_001174299
590
60761
G56
V
D
E
A
A
A
P
G
P
R
E
N
S
P
V
Rhesus Macaque
Macaca mulatta
XP_001082431
415
41783
S95
L
D
P
N
K
F
N
S
R
R
R
R
C
V
L
Dog
Lupus familis
XP_544059
354
36219
M40
S
G
P
R
A
A
G
M
L
A
W
Q
D
G
G
Cat
Felis silvestris
Mouse
Mus musculus
P42580
305
31994
Rat
Rattus norvegicus
P63156
327
35117
L22
H
R
A
G
S
P
A
L
P
K
G
D
P
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514461
324
33600
A19
L
S
M
A
A
G
Q
A
G
L
G
V
E
S
G
Chicken
Gallus gallus
P19601
232
25205
Frog
Xenopus laevis
Q91907
340
37176
S35
I
G
N
P
P
Q
P
S
P
G
H
F
V
Y
T
Zebra Danio
Brachydanio rerio
P22574
246
27686
Tiger Blowfish
Takifugu rubipres
O13074
288
32704
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001009577
432
47583
N93
Q
P
S
L
E
N
L
N
R
T
A
M
R
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.3
85
38.9
N.A.
42.3
26
N.A.
30.1
20.1
22.8
20.6
21.1
N.A.
N.A.
N.A.
28.9
Protein Similarity:
100
29.6
86.9
47.2
N.A.
49.8
35.2
N.A.
35.5
25
33.5
31.3
32.6
N.A.
N.A.
N.A.
38.1
P-Site Identity:
100
13.3
100
6.6
N.A.
0
6.6
N.A.
6.6
0
6.6
0
0
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
100
13.3
N.A.
0
20
N.A.
13.3
0
13.3
0
0
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
17
25
17
9
9
0
9
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% C
% Asp:
0
25
0
0
0
0
0
0
0
0
0
9
9
0
0
% D
% Glu:
0
0
9
0
9
0
0
0
0
0
9
0
9
0
0
% E
% Phe:
0
0
0
0
0
17
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
17
0
9
0
9
9
9
9
9
17
0
0
17
17
% G
% His:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
17
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
25
0
0
9
0
0
9
9
9
9
0
0
0
9
25
% L
% Met:
0
0
9
0
0
0
0
9
0
0
0
9
0
0
0
% M
% Asn:
0
0
9
17
0
9
17
9
0
0
0
9
0
0
0
% N
% Pro:
0
9
25
9
9
9
17
0
25
0
0
0
9
9
0
% P
% Gln:
9
0
0
0
0
9
9
0
0
0
0
9
0
0
0
% Q
% Arg:
0
9
0
9
0
0
0
0
25
25
17
17
9
0
9
% R
% Ser:
9
9
9
0
9
0
0
25
0
0
0
0
9
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
9
9
17
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _