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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NKX1-1 All Species: 4.24
Human Site: T133 Identified Species: 8.48
UniProt: Q15270 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15270 XP_931434.4 411 40659 T133 G E A E T N D T N G Y S S G G
Chimpanzee Pan troglodytes XP_001174299 590 60761 T126 L E N K F R A T R Y L S V C E
Rhesus Macaque Macaca mulatta XP_001082431 415 41783 V146 A L A G A G G V G A A G A E P
Dog Lupus familis XP_544059 354 36219 S88 A P R E A K K S L A E A D A G
Cat Felis silvestris
Mouse Mus musculus P42580 305 31994 A43 L P P V R L A A L E A K K S L
Rat Rattus norvegicus P63156 327 35117 R65 C L E T S T S R P G A A S G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514461 324 33600 S62 P A V H R T T S F S V L D I L
Chicken Gallus gallus P19601 232 25205
Frog Xenopus laevis Q91907 340 37176 H78 Q S T L S S A H H H H P I P S
Zebra Danio Brachydanio rerio P22574 246 27686
Tiger Blowfish Takifugu rubipres O13074 288 32704 S26 P C E E Y S Q S D Y L P N H S
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001009577 432 47583 K142 L D P H K F T K S S P T S G R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21.3 85 38.9 N.A. 42.3 26 N.A. 30.1 20.1 22.8 20.6 21.1 N.A. N.A. N.A. 28.9
Protein Similarity: 100 29.6 86.9 47.2 N.A. 49.8 35.2 N.A. 35.5 25 33.5 31.3 32.6 N.A. N.A. N.A. 38.1
P-Site Identity: 100 20 6.6 13.3 N.A. 0 20 N.A. 0 0 0 0 6.6 N.A. N.A. N.A. 13.3
P-Site Similarity: 100 26.6 13.3 26.6 N.A. 0 33.3 N.A. 6.6 0 26.6 0 33.3 N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 17 0 17 0 25 9 0 17 25 17 9 9 0 % A
% Cys: 9 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 9 0 0 0 0 9 0 9 0 0 0 17 0 0 % D
% Glu: 0 17 17 25 0 0 0 0 0 9 9 0 0 9 9 % E
% Phe: 0 0 0 0 9 9 0 0 9 0 0 0 0 0 0 % F
% Gly: 9 0 0 9 0 9 9 0 9 17 0 9 0 25 17 % G
% His: 0 0 0 17 0 0 0 9 9 9 9 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % I
% Lys: 0 0 0 9 9 9 9 9 0 0 0 9 9 0 0 % K
% Leu: 25 17 0 9 0 9 0 0 17 0 17 9 0 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 9 0 0 9 0 0 0 9 0 0 % N
% Pro: 17 17 17 0 0 0 0 0 9 0 9 17 0 9 17 % P
% Gln: 9 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 9 0 17 9 0 9 9 0 0 0 0 0 9 % R
% Ser: 0 9 0 0 17 17 9 25 9 17 0 17 25 9 17 % S
% Thr: 0 0 9 9 9 17 17 17 0 0 0 9 0 0 0 % T
% Val: 0 0 9 9 0 0 0 9 0 0 9 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 17 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _