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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF4
All Species:
4.55
Human Site:
S377
Identified Species:
11.11
UniProt:
Q15306
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15306
NP_002451.2
451
51772
S377
A
F
A
H
H
G
R
S
L
P
R
F
Q
V
T
Chimpanzee
Pan troglodytes
XP_518201
451
51722
S377
A
F
A
H
H
G
R
S
L
P
R
F
Q
V
T
Rhesus Macaque
Macaca mulatta
XP_001118967
649
72468
G553
L
L
G
H
L
E
R
G
V
V
L
W
M
A
P
Dog
Lupus familis
XP_546793
426
48688
D356
C
F
G
E
E
F
P
D
M
T
P
L
R
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q64287
450
51559
P377
V
F
A
H
H
G
R
P
A
P
R
F
Q
V
T
Rat
Rattus norvegicus
P23570
328
37046
L258
H
V
D
G
K
G
Y
L
L
N
E
P
G
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510417
651
74814
P577
V
F
A
H
H
G
R
P
L
P
R
F
Q
I
A
Chicken
Gallus gallus
Q90871
425
49152
E354
R
V
M
L
C
F
G
E
E
F
P
D
T
V
P
Frog
Xenopus laevis
NP_001087097
411
47602
F341
T
L
C
F
G
E
E
F
P
D
A
T
P
V
H
Zebra Danio
Brachydanio rerio
NP_001116182
460
52286
P387
G
F
I
H
H
G
R
P
M
P
R
S
Q
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
61.6
42.1
N.A.
92.2
22.3
N.A.
57.9
42.5
43.6
63.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
62.5
54
N.A.
95.7
37.4
N.A.
62.6
54.5
56.5
76.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
6.6
N.A.
80
13.3
N.A.
73.3
6.6
6.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
20
N.A.
80
13.3
N.A.
80
6.6
6.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
40
0
0
0
0
0
10
0
10
0
0
20
10
% A
% Cys:
10
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
10
0
10
0
10
0
0
0
% D
% Glu:
0
0
0
10
10
20
10
10
10
0
10
0
0
0
0
% E
% Phe:
0
60
0
10
0
20
0
10
0
10
0
40
0
0
0
% F
% Gly:
10
0
20
10
10
60
10
10
0
0
0
0
10
0
0
% G
% His:
10
0
0
60
50
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
10
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
10
20
0
10
10
0
0
10
40
0
10
10
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
20
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
30
10
50
20
10
10
0
20
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
10
% Q
% Arg:
10
0
0
0
0
0
60
0
0
0
50
0
10
0
0
% R
% Ser:
0
0
0
0
0
0
0
20
0
0
0
10
0
10
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
10
0
10
10
0
30
% T
% Val:
20
20
0
0
0
0
0
0
10
10
0
0
0
60
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _