KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F5
All Species:
21.52
Human Site:
S236
Identified Species:
33.81
UniProt:
Q15329
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15329
NP_001077057.1
346
37610
S236
I
N
K
E
S
S
S
S
K
P
V
V
F
P
V
Chimpanzee
Pan troglodytes
XP_511025
426
45548
S221
V
N
K
E
A
W
S
S
P
P
V
A
V
P
V
Rhesus Macaque
Macaca mulatta
XP_001094919
346
37697
S236
I
N
K
E
S
S
S
S
K
P
V
V
F
P
V
Dog
Lupus familis
XP_853833
304
33793
V198
E
S
S
S
S
K
P
V
V
F
P
V
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61502
335
36766
S226
I
N
K
E
S
S
S
S
K
P
V
V
F
P
V
Rat
Rattus norvegicus
Q62814
300
33206
P197
S
S
K
P
V
V
F
P
V
P
P
P
D
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517985
227
25092
P123
K
E
S
S
S
S
K
P
V
V
F
P
V
P
P
Chicken
Gallus gallus
Q90977
403
43534
E295
S
P
F
K
A
P
A
E
E
L
S
P
G
S
S
Frog
Xenopus laevis
NP_001086706
375
40890
S198
V
N
K
D
T
S
S
S
A
P
V
V
V
P
V
Zebra Danio
Brachydanio rerio
NP_998597
393
42365
S198
V
N
K
D
P
S
S
S
S
P
V
V
L
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
L554
L
N
Q
L
V
P
T
L
T
N
P
V
V
R
T
Honey Bee
Apis mellifera
XP_624285
300
34327
P197
I
K
V
Y
M
I
Q
P
E
L
A
K
T
Y
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799123
356
39484
Q246
V
V
V
Q
Q
Q
Q
Q
Q
V
R
Q
P
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130952
446
48668
S317
V
S
Q
F
E
E
M
S
G
M
E
T
P
P
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565831
483
52579
F353
V
S
E
F
E
G
K
F
E
D
T
N
G
S
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
97.9
78.9
N.A.
88.1
82.6
N.A.
57.2
33
58.1
56.2
N.A.
20.6
41
N.A.
51.9
Protein Similarity:
100
62.2
98.5
82.6
N.A.
90.1
84.3
N.A.
60.6
49.6
68.8
66.1
N.A.
29.6
55.2
N.A.
65.1
P-Site Identity:
100
60
100
20
N.A.
100
13.3
N.A.
20
0
66.6
66.6
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
73.3
100
26.6
N.A.
100
26.6
N.A.
20
26.6
86.6
80
N.A.
33.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
31.3
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
45
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
14
0
7
0
7
0
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
14
0
0
0
0
0
7
0
0
7
7
7
% D
% Glu:
7
7
7
27
14
7
0
7
20
0
7
0
0
0
0
% E
% Phe:
0
0
7
14
0
0
7
7
0
7
7
0
20
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
7
0
0
0
14
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
27
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
7
47
7
0
7
14
0
20
0
0
7
0
0
0
% K
% Leu:
7
0
0
7
0
0
0
7
0
14
0
0
7
0
7
% L
% Met:
0
0
0
0
7
0
7
0
0
7
0
0
0
0
0
% M
% Asn:
0
47
0
0
0
0
0
0
0
7
0
7
0
0
0
% N
% Pro:
0
7
0
7
7
14
7
20
7
47
20
20
20
60
20
% P
% Gln:
0
0
14
7
7
7
14
7
7
0
0
7
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
7
% R
% Ser:
14
27
14
14
34
40
40
47
7
0
7
0
0
14
7
% S
% Thr:
0
0
0
0
7
0
7
0
7
0
7
7
7
7
7
% T
% Val:
40
7
14
0
14
7
0
7
20
14
40
47
27
0
40
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _