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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F5
All Species:
14.24
Human Site:
S318
Identified Species:
22.38
UniProt:
Q15329
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15329
NP_001077057.1
346
37610
S318
V
F
P
L
L
R
L
S
P
T
P
A
D
D
Y
Chimpanzee
Pan troglodytes
XP_511025
426
45548
L303
D
S
K
D
S
G
E
L
S
S
L
P
L
G
P
Rhesus Macaque
Macaca mulatta
XP_001094919
346
37697
S318
V
F
P
L
L
R
L
S
P
T
P
A
D
D
Y
Dog
Lupus familis
XP_853833
304
33793
A280
L
R
L
S
P
T
P
A
D
D
Y
N
F
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61502
335
36766
P308
F
P
L
L
R
L
S
P
T
P
A
D
D
Y
N
Rat
Rattus norvegicus
Q62814
300
33206
Y279
S
P
T
P
A
D
D
Y
N
F
N
L
D
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517985
227
25092
D205
L
S
P
T
P
A
D
D
Y
N
F
N
L
D
D
Chicken
Gallus gallus
Q90977
403
43534
Y377
S
P
P
Q
P
Q
D
Y
H
F
G
L
E
E
G
Frog
Xenopus laevis
NP_001086706
375
40890
S280
I
D
T
C
P
L
Q
S
S
A
S
L
D
N
S
Zebra Danio
Brachydanio rerio
NP_998597
393
42365
T280
A
D
T
D
I
S
S
T
S
T
P
D
T
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
S636
S
S
S
N
N
S
K
S
Q
P
P
T
I
G
Y
Honey Bee
Apis mellifera
XP_624285
300
34327
K279
L
S
P
P
P
S
E
K
D
Y
H
F
N
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799123
356
39484
S328
T
Y
P
L
L
R
L
S
P
A
P
N
D
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130952
446
48668
S399
L
S
D
N
T
G
V
S
M
T
N
M
W
E
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565831
483
52579
W435
E
N
D
E
S
D
Y
W
L
L
S
N
A
E
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
97.9
78.9
N.A.
88.1
82.6
N.A.
57.2
33
58.1
56.2
N.A.
20.6
41
N.A.
51.9
Protein Similarity:
100
62.2
98.5
82.6
N.A.
90.1
84.3
N.A.
60.6
49.6
68.8
66.1
N.A.
29.6
55.2
N.A.
65.1
P-Site Identity:
100
0
100
0
N.A.
13.3
13.3
N.A.
13.3
6.6
13.3
13.3
N.A.
20
6.6
N.A.
60
P-Site Similarity:
100
6.6
100
20
N.A.
13.3
13.3
N.A.
20
26.6
26.6
26.6
N.A.
20
20
N.A.
66.6
Percent
Protein Identity:
N.A.
31.3
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
45
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
7
0
7
0
14
7
14
7
0
7
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
14
14
0
14
20
7
14
7
0
14
40
27
14
% D
% Glu:
7
0
0
7
0
0
14
0
0
0
0
0
7
20
0
% E
% Phe:
7
14
0
0
0
0
0
0
0
14
7
7
7
0
0
% F
% Gly:
0
0
0
0
0
14
0
0
0
0
7
0
0
14
7
% G
% His:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% H
% Ile:
7
0
0
0
7
0
0
0
0
0
0
0
7
0
7
% I
% Lys:
0
0
7
0
0
0
7
7
0
0
0
0
0
0
0
% K
% Leu:
27
0
14
27
20
14
20
7
7
7
7
20
14
7
7
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% M
% Asn:
0
7
0
14
7
0
0
0
7
7
14
27
7
14
14
% N
% Pro:
0
20
40
14
34
0
7
7
20
14
34
7
0
0
7
% P
% Gln:
0
0
0
7
0
7
7
0
7
0
0
0
0
7
0
% Q
% Arg:
0
7
0
0
7
20
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
34
7
7
14
20
14
40
20
7
14
0
0
0
14
% S
% Thr:
7
0
20
7
7
7
0
7
7
27
0
7
7
7
7
% T
% Val:
14
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% W
% Tyr:
0
7
0
0
0
0
7
14
7
7
7
0
0
7
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _