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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED2
All Species:
49.39
Human Site:
S77
Identified Species:
77.62
UniProt:
Q15363
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15363
NP_006806.1
201
22761
S77
Y
K
G
D
R
E
S
S
G
K
Y
T
F
A
A
Chimpanzee
Pan troglodytes
XP_001173027
201
22773
S77
Y
K
G
D
R
E
S
S
G
K
Y
T
F
A
A
Rhesus Macaque
Macaca mulatta
XP_001098453
868
97849
S202
Y
K
G
D
R
E
S
S
G
K
Y
T
F
A
A
Dog
Lupus familis
XP_858034
742
84495
S77
Y
K
G
D
R
E
S
S
G
K
Y
T
F
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0Q3
201
22687
S77
Y
K
G
D
R
E
S
S
G
K
Y
T
F
A
A
Rat
Rattus norvegicus
Q63524
201
22715
S77
Y
K
G
D
R
E
S
S
G
K
Y
T
F
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507202
200
23189
S76
Y
K
G
D
R
E
S
S
G
K
Y
T
F
A
A
Chicken
Gallus gallus
NP_001006186
201
22584
S77
Y
K
G
D
R
E
S
S
G
K
Y
T
F
A
A
Frog
Xenopus laevis
NP_001080619
201
22823
S77
Y
K
G
D
R
E
S
S
G
K
Y
T
F
A
A
Zebra Danio
Brachydanio rerio
NP_955842
201
22912
S77
Y
K
G
D
R
E
S
S
G
K
Y
S
V
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9I7K5
216
25140
Q88
L
S
R
V
Y
S
S
Q
G
R
I
S
F
T
S
Honey Bee
Apis mellifera
XP_624979
205
23392
S76
Y
Q
G
D
Q
E
S
S
G
K
Y
T
F
A
T
Nematode Worm
Caenorhab. elegans
O17528
203
22968
S75
Y
K
G
E
R
E
S
S
G
K
F
T
F
A
A
Sea Urchin
Strong. purpuratus
XP_791284
189
21523
A72
N
G
K
Y
T
F
A
A
H
M
D
G
V
Y
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32803
203
23314
H83
K
T
V
R
D
T
S
H
G
E
I
T
L
S
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
22.9
26.5
N.A.
99
99.5
N.A.
73.1
93
95.5
91
N.A.
27.3
60.4
65.5
71.1
Protein Similarity:
100
99.5
23.1
26.9
N.A.
99
99.5
N.A.
74.6
94.5
97
94
N.A.
46.2
79
81.2
84.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
86.6
N.A.
20
80
86.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
40
93.3
100
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
7
0
0
0
0
0
80
80
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
74
7
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
0
0
0
7
0
80
0
0
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
7
0
80
0
0
% F
% Gly:
0
7
80
0
0
0
0
0
94
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% I
% Lys:
7
74
7
0
0
0
0
0
0
80
0
0
0
0
0
% K
% Leu:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
7
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
7
74
0
0
0
0
7
0
0
0
0
7
% R
% Ser:
0
7
0
0
0
7
94
80
0
0
0
14
0
7
7
% S
% Thr:
0
7
0
0
7
7
0
0
0
0
0
80
0
7
7
% T
% Val:
0
0
7
7
0
0
0
0
0
0
0
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
80
0
0
7
7
0
0
0
0
0
74
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _