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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED2
All Species:
54.24
Human Site:
Y150
Identified Species:
85.24
UniProt:
Q15363
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15363
NP_006806.1
201
22761
Y150
A
V
K
H
E
Q
E
Y
M
E
V
R
E
R
I
Chimpanzee
Pan troglodytes
XP_001173027
201
22773
Y150
A
V
K
H
E
Q
E
Y
M
E
V
R
E
R
I
Rhesus Macaque
Macaca mulatta
XP_001098453
868
97849
Y275
A
V
K
H
E
Q
E
Y
M
E
V
R
E
R
I
Dog
Lupus familis
XP_858034
742
84495
Y150
A
V
K
H
E
Q
E
Y
M
E
V
R
E
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0Q3
201
22687
Y150
A
V
K
H
E
Q
E
Y
M
E
V
R
E
R
I
Rat
Rattus norvegicus
Q63524
201
22715
Y150
A
V
K
H
E
Q
E
Y
M
E
V
R
E
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507202
200
23189
Y149
A
V
K
H
E
Q
E
Y
M
E
V
R
E
R
I
Chicken
Gallus gallus
NP_001006186
201
22584
Y150
A
V
K
H
E
Q
E
Y
M
E
V
R
E
R
I
Frog
Xenopus laevis
NP_001080619
201
22823
Y150
A
V
K
H
E
Q
E
Y
M
E
V
R
E
R
I
Zebra Danio
Brachydanio rerio
NP_955842
201
22912
Y150
A
V
K
H
E
Q
E
Y
M
E
V
R
E
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9I7K5
216
25140
Y165
Q
I
T
K
E
Q
N
Y
Q
R
Y
R
E
E
R
Honey Bee
Apis mellifera
XP_624979
205
23392
Y154
G
V
K
N
E
Q
E
Y
M
Q
V
R
D
R
N
Nematode Worm
Caenorhab. elegans
O17528
203
22968
Y152
S
V
K
H
E
Q
E
Y
M
E
V
R
E
R
V
Sea Urchin
Strong. purpuratus
XP_791284
189
21523
R142
E
L
E
Y
M
E
V
R
E
R
V
H
R
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32803
203
23314
Y152
E
V
K
D
E
Q
S
Y
I
V
I
R
E
R
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
22.9
26.5
N.A.
99
99.5
N.A.
73.1
93
95.5
91
N.A.
27.3
60.4
65.5
71.1
Protein Similarity:
100
99.5
23.1
26.9
N.A.
99
99.5
N.A.
74.6
94.5
97
94
N.A.
46.2
79
81.2
84.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
33.3
66.6
86.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
40
86.6
100
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% D
% Glu:
14
0
7
0
94
7
80
0
7
74
0
0
87
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
74
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
7
0
7
0
0
0
74
% I
% Lys:
0
0
87
7
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
7
0
0
0
80
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
94
0
0
7
7
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
0
14
0
94
7
87
7
% R
% Ser:
7
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% S
% Thr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% T
% Val:
0
87
0
0
0
0
7
0
0
7
87
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
94
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _