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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED2
All Species:
48.48
Human Site:
Y70
Identified Species:
76.19
UniProt:
Q15363
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15363
NP_006806.1
201
22761
Y70
G
P
D
N
K
G
I
Y
K
G
D
R
E
S
S
Chimpanzee
Pan troglodytes
XP_001173027
201
22773
Y70
G
P
D
N
K
G
I
Y
K
G
D
R
E
S
S
Rhesus Macaque
Macaca mulatta
XP_001098453
868
97849
Y195
G
P
D
N
K
G
I
Y
K
G
D
R
E
S
S
Dog
Lupus familis
XP_858034
742
84495
Y70
G
P
D
N
K
G
I
Y
K
G
D
R
E
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0Q3
201
22687
Y70
G
P
D
N
K
G
I
Y
K
G
D
R
E
S
S
Rat
Rattus norvegicus
Q63524
201
22715
Y70
G
P
D
N
K
G
I
Y
K
G
D
R
E
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507202
200
23189
Y69
G
P
D
N
K
G
I
Y
K
G
D
R
E
S
S
Chicken
Gallus gallus
NP_001006186
201
22584
Y70
G
P
D
N
K
G
I
Y
K
G
D
R
E
S
S
Frog
Xenopus laevis
NP_001080619
201
22823
Y70
G
P
D
N
K
G
I
Y
K
G
D
R
E
S
S
Zebra Danio
Brachydanio rerio
NP_955842
201
22912
Y70
G
P
D
G
K
Q
I
Y
K
G
D
R
E
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9I7K5
216
25140
L81
D
S
D
D
K
I
V
L
S
R
V
Y
S
S
Q
Honey Bee
Apis mellifera
XP_624979
205
23392
Y69
G
P
D
G
K
I
I
Y
Q
G
D
Q
E
S
S
Nematode Worm
Caenorhab. elegans
O17528
203
22968
Y68
G
P
D
N
K
E
I
Y
K
G
E
R
E
S
S
Sea Urchin
Strong. purpuratus
XP_791284
189
21523
N65
H
T
G
E
R
E
S
N
G
K
Y
T
F
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32803
203
23314
K76
P
E
R
H
E
V
L
K
T
V
R
D
T
S
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
22.9
26.5
N.A.
99
99.5
N.A.
73.1
93
95.5
91
N.A.
27.3
60.4
65.5
71.1
Protein Similarity:
100
99.5
23.1
26.9
N.A.
99
99.5
N.A.
74.6
94.5
97
94
N.A.
46.2
79
81.2
84.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
86.6
N.A.
20
73.3
86.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
86.6
N.A.
33.3
86.6
93.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
87
7
0
0
0
0
0
0
74
7
0
0
0
% D
% Glu:
0
7
0
7
7
14
0
0
0
0
7
0
80
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
80
0
7
14
0
60
0
0
7
80
0
0
0
0
0
% G
% His:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
14
80
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
87
0
0
7
74
7
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
67
0
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
7
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
7
0
0
7
0
0
7
% Q
% Arg:
0
0
7
0
7
0
0
0
0
7
7
74
0
0
0
% R
% Ser:
0
7
0
0
0
0
7
0
7
0
0
0
7
94
80
% S
% Thr:
0
7
0
0
0
0
0
0
7
0
0
7
7
0
0
% T
% Val:
0
0
0
0
0
7
7
0
0
7
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _