KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RHEB
All Species:
24.85
Human Site:
S175
Identified Species:
45.56
UniProt:
Q15382
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15382
NP_005605.1
184
20497
S175
E
K
M
D
G
A
A
S
Q
G
K
S
S
C
S
Chimpanzee
Pan troglodytes
XP_507769
184
20380
S175
E
K
M
D
G
A
A
S
Q
G
K
S
S
C
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q921J2
184
20433
S175
E
K
I
D
G
A
A
S
Q
G
K
S
S
C
S
Rat
Rattus norvegicus
Q62639
184
20461
S175
E
K
I
D
G
A
A
S
Q
G
K
S
S
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513157
385
41817
S376
E
K
I
D
G
S
A
S
Q
G
K
S
S
C
S
Chicken
Gallus gallus
XP_001232988
184
20402
S175
E
K
I
D
G
A
A
S
Q
G
K
S
S
C
S
Frog
Xenopus laevis
Q7ZXH7
184
20815
A175
K
T
P
V
P
G
K
A
R
K
K
S
T
C
H
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
P175
K
T
P
V
T
G
K
P
R
K
K
S
T
C
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VND8
182
20712
P173
I
E
N
E
N
G
N
P
Q
E
K
S
G
C
L
Honey Bee
Apis mellifera
XP_392564
182
20478
V173
I
E
K
A
D
G
N
V
Q
E
K
S
N
C
I
Nematode Worm
Caenorhab. elegans
P34443
207
23677
T184
S
R
G
N
L
S
P
T
E
R
P
N
G
N
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25378
209
23319
A200
E
G
T
L
G
L
D
A
E
N
N
N
K
C
S
Red Bread Mold
Neurospora crassa
P22126
213
24008
E200
K
Q
M
D
V
G
D
E
D
V
Q
A
G
C
C
Conservation
Percent
Protein Identity:
100
99.4
N.A.
N.A.
N.A.
98.9
99.4
N.A.
46.2
98.3
37.5
38
N.A.
63.5
65.7
40
N.A.
Protein Similarity:
100
99.4
N.A.
N.A.
N.A.
100
100
N.A.
47.7
99.4
63
63.5
N.A.
80.4
84.2
61.3
N.A.
P-Site Identity:
100
100
N.A.
N.A.
N.A.
93.3
93.3
N.A.
86.6
93.3
20
20
N.A.
26.6
26.6
6.6
N.A.
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
100
100
46.6
40
N.A.
40
40
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.8
34.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
59.8
56.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
39
47
16
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
93
8
% C
% Asp:
0
0
0
54
8
0
16
0
8
0
0
0
0
0
0
% D
% Glu:
54
16
0
8
0
0
0
8
16
16
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
54
39
0
0
0
47
0
0
24
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
16
0
31
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
24
47
8
0
0
0
16
0
0
16
77
0
8
0
0
% K
% Leu:
0
0
0
8
8
8
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
8
0
16
0
0
8
8
16
8
8
0
% N
% Pro:
0
0
16
0
8
0
8
16
0
0
8
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
62
0
8
0
0
0
8
% Q
% Arg:
0
8
0
0
0
0
0
0
16
8
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
16
0
47
0
0
0
77
47
0
62
% S
% Thr:
0
16
8
0
8
0
0
8
0
0
0
0
16
0
0
% T
% Val:
0
0
0
16
8
0
0
8
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _