Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RHEB All Species: 30.61
Human Site: S34 Identified Species: 56.11
UniProt: Q15382 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15382 NP_005605.1 184 20497 S34 V E G Q F V D S Y D P T I E N
Chimpanzee Pan troglodytes XP_507769 184 20380 S34 V E G Q F V D S Y D P T I E N
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q921J2 184 20433 S34 V E G Q F V D S Y D P T I E N
Rat Rattus norvegicus Q62639 184 20461 S34 V E G Q F V D S Y D P T I E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513157 385 41817 S235 V E G Q F V D S Y D P T I E N
Chicken Gallus gallus XP_001232988 184 20402 S34 V E G Q F V D S Y D P T I E N
Frog Xenopus laevis Q7ZXH7 184 20815 G48 R K Q V E V D G Q Q C M L E I
Zebra Danio Brachydanio rerio Q6TEN1 184 20809 G48 R K Q V E V D G Q Q C M L E I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VND8 182 20712 S50 T K I E R V K S Q D Y I V K L
Honey Bee Apis mellifera XP_392564 182 20478 S45 I E N T F T K S T R V N S Q D
Nematode Worm Caenorhab. elegans P34443 207 23677 R41 T Q N I F P E R Y E S T I E D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25378 209 23319 S44 V E S R F V E S Y Y P T I E N
Red Bread Mold Neurospora crassa P22126 213 24008 E36 I Q G H F L D E Y D P T I E D
Conservation
Percent
Protein Identity: 100 99.4 N.A. N.A. N.A. 98.9 99.4 N.A. 46.2 98.3 37.5 38 N.A. 63.5 65.7 40 N.A.
Protein Similarity: 100 99.4 N.A. N.A. N.A. 100 100 N.A. 47.7 99.4 63 63.5 N.A. 80.4 84.2 61.3 N.A.
P-Site Identity: 100 100 N.A. N.A. N.A. 100 100 N.A. 100 100 20 20 N.A. 20 20 33.3 N.A.
P-Site Similarity: 100 100 N.A. N.A. N.A. 100 100 N.A. 100 100 33.3 33.3 N.A. 46.6 40 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.8 34.7
Protein Similarity: N.A. N.A. N.A. N.A. 59.8 56.3
P-Site Identity: N.A. N.A. N.A. N.A. 73.3 60
P-Site Similarity: N.A. N.A. N.A. N.A. 86.6 86.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 70 0 0 62 0 0 0 0 24 % D
% Glu: 0 62 0 8 16 0 16 8 0 8 0 0 0 85 0 % E
% Phe: 0 0 0 0 77 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 54 0 0 0 0 16 0 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 16 0 8 8 0 0 0 0 0 0 0 8 70 0 16 % I
% Lys: 0 24 0 0 0 0 16 0 0 0 0 0 0 8 0 % K
% Leu: 0 0 0 0 0 8 0 0 0 0 0 0 16 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % M
% Asn: 0 0 16 0 0 0 0 0 0 0 0 8 0 0 54 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 62 0 0 0 0 % P
% Gln: 0 16 16 47 0 0 0 0 24 16 0 0 0 8 0 % Q
% Arg: 16 0 0 8 8 0 0 8 0 8 0 0 0 0 0 % R
% Ser: 0 0 8 0 0 0 0 70 0 0 8 0 8 0 0 % S
% Thr: 16 0 0 8 0 8 0 0 8 0 0 70 0 0 0 % T
% Val: 54 0 0 16 0 77 0 0 0 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 70 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _