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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RHEB
All Species:
27.27
Human Site:
T73
Identified Species:
50
UniProt:
Q15382
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15382
NP_005605.1
184
20497
T73
E
Y
S
I
F
P
Q
T
Y
S
I
D
I
N
G
Chimpanzee
Pan troglodytes
XP_507769
184
20380
T73
E
Y
S
I
F
P
Q
T
Y
S
I
D
I
N
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q921J2
184
20433
T73
E
Y
S
I
F
P
Q
T
Y
S
I
D
I
N
G
Rat
Rattus norvegicus
Q62639
184
20461
T73
E
Y
S
I
F
P
Q
T
Y
S
I
D
I
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513157
385
41817
T274
E
Y
S
I
F
P
Q
T
Y
S
I
D
I
N
G
Chicken
Gallus gallus
XP_001232988
184
20402
T73
E
Y
S
I
F
P
Q
T
Y
S
I
D
I
N
G
Frog
Xenopus laevis
Q7ZXH7
184
20815
Q87
L
V
Y
S
I
T
A
Q
S
T
F
N
D
L
Q
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
Q87
L
V
Y
S
I
T
A
Q
S
T
F
N
D
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VND8
182
20712
Q89
L
V
Y
S
I
T
S
Q
K
S
F
E
V
V
K
Honey Bee
Apis mellifera
XP_392564
182
20478
Y84
I
H
G
Y
V
L
V
Y
S
I
T
S
A
K
S
Nematode Worm
Caenorhab. elegans
P34443
207
23677
S80
E
Y
T
V
F
P
R
S
C
S
L
D
I
N
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25378
209
23319
K83
E
V
S
L
L
N
I
K
S
L
T
G
V
R
G
Red Bread Mold
Neurospora crassa
P22126
213
24008
Q75
E
Y
S
A
M
R
E
Q
Y
M
R
T
G
E
G
Conservation
Percent
Protein Identity:
100
99.4
N.A.
N.A.
N.A.
98.9
99.4
N.A.
46.2
98.3
37.5
38
N.A.
63.5
65.7
40
N.A.
Protein Similarity:
100
99.4
N.A.
N.A.
N.A.
100
100
N.A.
47.7
99.4
63
63.5
N.A.
80.4
84.2
61.3
N.A.
P-Site Identity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
100
100
0
0
N.A.
6.6
0
60
N.A.
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
100
100
13.3
13.3
N.A.
20
6.6
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.8
34.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
59.8
56.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
16
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
54
16
0
0
% D
% Glu:
70
0
0
0
0
0
8
0
0
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
54
0
0
0
0
0
24
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
8
8
0
70
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
47
24
0
8
0
0
8
47
0
54
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
8
0
0
0
0
8
8
% K
% Leu:
24
0
0
8
8
8
0
0
0
8
8
0
0
16
0
% L
% Met:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
16
0
54
0
% N
% Pro:
0
0
0
0
0
54
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
47
31
0
0
0
0
0
0
16
% Q
% Arg:
0
0
0
0
0
8
8
0
0
0
8
0
0
8
0
% R
% Ser:
0
0
62
24
0
0
8
8
31
62
0
8
0
0
8
% S
% Thr:
0
0
8
0
0
24
0
47
0
16
16
8
0
0
0
% T
% Val:
0
31
0
8
8
0
8
0
0
0
0
0
16
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
62
24
8
0
0
0
8
54
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _