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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RHEB
All Species:
22.12
Human Site:
Y14
Identified Species:
40.56
UniProt:
Q15382
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15382
NP_005605.1
184
20497
Y14
R
K
I
A
I
L
G
Y
R
S
V
G
K
S
S
Chimpanzee
Pan troglodytes
XP_507769
184
20380
Y14
R
K
I
A
I
L
G
Y
R
S
V
G
K
S
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q921J2
184
20433
Y14
R
K
I
A
I
L
G
Y
R
S
V
G
K
S
S
Rat
Rattus norvegicus
Q62639
184
20461
Y14
R
K
I
A
I
L
G
Y
R
S
V
G
K
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513157
385
41817
F215
R
Q
V
A
R
L
G
F
S
F
L
G
K
S
S
Chicken
Gallus gallus
XP_001232988
184
20402
Y14
R
K
I
A
I
L
G
Y
R
S
V
G
K
S
S
Frog
Xenopus laevis
Q7ZXH7
184
20815
F28
V
Q
F
V
Q
G
I
F
V
E
K
Y
D
P
T
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
F28
V
Q
F
V
Q
G
I
F
V
E
K
Y
D
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VND8
182
20712
F30
I
Q
F
V
E
G
Q
F
V
D
S
Y
D
P
T
Honey Bee
Apis mellifera
XP_392564
182
20478
F25
K
S
S
L
S
I
Q
F
V
E
G
Q
F
V
D
Nematode Worm
Caenorhab. elegans
P34443
207
23677
Y21
R
K
V
A
V
M
G
Y
P
H
V
G
K
S
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25378
209
23319
A24
R
K
I
A
L
I
G
A
R
N
V
G
K
T
T
Red Bread Mold
Neurospora crassa
P22126
213
24008
G16
Y
K
L
V
V
V
G
G
G
G
V
G
K
S
C
Conservation
Percent
Protein Identity:
100
99.4
N.A.
N.A.
N.A.
98.9
99.4
N.A.
46.2
98.3
37.5
38
N.A.
63.5
65.7
40
N.A.
Protein Similarity:
100
99.4
N.A.
N.A.
N.A.
100
100
N.A.
47.7
99.4
63
63.5
N.A.
80.4
84.2
61.3
N.A.
P-Site Identity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
53.3
100
0
0
N.A.
0
0
60
N.A.
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
80
100
20
20
N.A.
20
20
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.8
34.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
59.8
56.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
62
0
0
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
24
0
8
% D
% Glu:
0
0
0
0
8
0
0
0
0
24
0
0
0
0
0
% E
% Phe:
0
0
24
0
0
0
0
39
0
8
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
24
70
8
8
8
8
70
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
47
0
39
16
16
0
0
0
0
0
0
0
0
% I
% Lys:
8
62
0
0
0
0
0
0
0
0
16
0
70
0
0
% K
% Leu:
0
0
8
8
8
47
0
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
24
0
% P
% Gln:
0
31
0
0
16
0
16
0
0
0
0
8
0
0
0
% Q
% Arg:
62
0
0
0
8
0
0
0
47
0
0
0
0
0
0
% R
% Ser:
0
8
8
0
8
0
0
0
8
39
8
0
0
62
47
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
31
% T
% Val:
16
0
16
31
16
8
0
0
31
0
62
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
47
0
0
0
24
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _