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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3C
All Species:
22.42
Human Site:
S126
Identified Species:
35.24
UniProt:
Q15386
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15386
NP_055486.2
1083
123923
S126
Q
N
L
I
K
H
S
S
L
F
V
K
Q
L
D
Chimpanzee
Pan troglodytes
XP_528010
1089
124652
S132
Q
N
L
I
K
H
S
S
L
F
V
K
Q
L
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539937
1088
124202
S126
Q
N
L
I
K
H
S
S
L
F
V
Q
Q
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80U95
1083
123957
S126
Q
N
L
I
K
H
S
S
L
F
V
K
Q
L
D
Rat
Rattus norvegicus
Q62940
887
102376
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510756
1084
124281
S126
Q
N
L
I
K
Q
N
S
Q
F
V
K
Q
L
D
Chicken
Gallus gallus
NP_001026138
1084
124128
S126
Q
N
L
I
K
Q
S
S
Q
F
V
K
Q
L
D
Frog
Xenopus laevis
Q6DCL5
944
106566
R63
D
V
N
Y
A
F
G
R
V
K
R
S
L
L
H
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611896
1122
128925
I119
L
I
E
V
C
Q
Q
I
L
R
Q
P
A
R
L
Honey Bee
Apis mellifera
XP_396547
1033
119022
R119
S
D
W
L
W
R
L
R
W
I
L
R
M
C
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797123
1037
118587
T125
L
L
E
A
P
S
S
T
P
V
A
M
P
L
R
Poplar Tree
Populus trichocarpa
XP_002314972
1027
117409
R119
T
I
L
V
E
T
C
R
L
L
L
Q
N
V
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWB8
1029
117643
L120
I
L
V
E
T
C
R
L
L
Q
S
F
V
D
S
Baker's Yeast
Sacchar. cerevisiae
P53119
910
105547
K29
S
K
K
D
L
L
E
K
A
K
R
E
R
E
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
N.A.
95.4
N.A.
93.3
22.1
N.A.
91.4
90.6
22.8
22.5
N.A.
39.7
43
N.A.
44.2
Protein Similarity:
100
98.1
N.A.
97.4
N.A.
97.2
38.4
N.A.
95.6
94.8
39
38.3
N.A.
61
62.7
N.A.
61.6
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
0
N.A.
80
86.6
6.6
0
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
0
N.A.
86.6
86.6
13.3
0
N.A.
13.3
26.6
N.A.
20
Percent
Protein Identity:
28.3
N.A.
N.A.
28.7
26.7
N.A.
Protein Similarity:
47
N.A.
N.A.
49
44.9
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
0
0
0
7
0
7
0
7
0
0
% A
% Cys:
0
0
0
0
7
7
7
0
0
0
0
0
0
7
0
% C
% Asp:
7
7
0
7
0
0
0
0
0
0
0
0
0
7
40
% D
% Glu:
0
0
14
7
7
0
7
0
0
0
0
7
0
7
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
40
0
7
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
27
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
14
0
40
0
0
0
7
0
7
0
0
0
0
0
% I
% Lys:
0
7
7
0
40
0
0
7
0
14
0
34
0
0
0
% K
% Leu:
14
14
47
7
7
7
7
7
47
7
14
0
7
54
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
7
% M
% Asn:
0
40
7
0
0
0
7
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
7
0
0
0
7
0
0
7
7
0
0
% P
% Gln:
40
0
0
0
0
20
7
0
14
7
7
14
40
0
0
% Q
% Arg:
0
0
0
0
0
7
7
20
0
7
14
7
7
7
20
% R
% Ser:
14
0
0
0
0
7
40
40
0
0
7
7
0
0
7
% S
% Thr:
7
0
0
0
7
7
0
7
0
0
0
0
0
0
0
% T
% Val:
0
7
7
14
0
0
0
0
7
7
40
0
7
7
0
% V
% Trp:
0
0
7
0
7
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _