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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3C
All Species:
22.73
Human Site:
S221
Identified Species:
35.71
UniProt:
Q15386
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15386
NP_055486.2
1083
123923
S221
L
I
N
S
K
L
P
S
S
I
E
Y
S
D
L
Chimpanzee
Pan troglodytes
XP_528010
1089
124652
S227
L
I
N
S
K
L
P
S
S
I
E
Y
S
D
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539937
1088
124202
S221
L
I
N
S
K
L
P
S
S
I
E
Y
S
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80U95
1083
123957
S221
L
I
N
S
K
L
P
S
S
I
E
Y
S
D
L
Rat
Rattus norvegicus
Q62940
887
102376
R101
G
A
S
D
P
Y
V
R
V
T
L
Y
D
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510756
1084
124281
S221
L
I
N
S
K
L
P
S
S
I
E
Y
S
D
V
Chicken
Gallus gallus
NP_001026138
1084
124128
S221
L
I
N
S
K
L
P
S
S
I
E
Y
S
D
V
Frog
Xenopus laevis
Q6DCL5
944
106566
D158
V
Q
H
V
T
N
V
D
V
E
D
A
M
G
Q
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611896
1122
128925
P214
L
L
D
D
K
C
P
P
L
D
G
E
T
L
H
Honey Bee
Apis mellifera
XP_396547
1033
119022
I214
S
K
C
L
V
D
M
I
K
R
P
L
D
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797123
1037
118587
I220
A
F
K
V
Q
R
N
I
A
L
C
S
L
C
Q
Poplar Tree
Populus trichocarpa
XP_002314972
1027
117409
N214
V
G
Y
L
L
Q
R
N
A
F
A
L
F
R
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWB8
1029
117643
F215
Y
L
Q
K
R
K
V
F
K
L
V
R
E
M
V
Baker's Yeast
Sacchar. cerevisiae
P53119
910
105547
Q124
L
S
L
L
K
L
Y
Q
D
D
A
L
V
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
N.A.
95.4
N.A.
93.3
22.1
N.A.
91.4
90.6
22.8
22.5
N.A.
39.7
43
N.A.
44.2
Protein Similarity:
100
98.1
N.A.
97.4
N.A.
97.2
38.4
N.A.
95.6
94.8
39
38.3
N.A.
61
62.7
N.A.
61.6
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
93.3
93.3
0
0
N.A.
20
0
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
100
100
20
0
N.A.
40
6.6
N.A.
20
Percent
Protein Identity:
28.3
N.A.
N.A.
28.7
26.7
N.A.
Protein Similarity:
47
N.A.
N.A.
49
44.9
N.A.
P-Site Identity:
0
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
0
0
14
0
14
7
0
7
0
% A
% Cys:
0
0
7
0
0
7
0
0
0
0
7
0
0
7
0
% C
% Asp:
0
0
7
14
0
7
0
7
7
14
7
0
14
40
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
7
40
7
7
0
14
% E
% Phe:
0
7
0
0
0
0
0
7
0
7
0
0
7
0
0
% F
% Gly:
7
7
0
0
0
0
0
0
0
0
7
0
0
7
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
40
0
0
0
0
0
14
0
40
0
0
0
0
7
% I
% Lys:
0
7
7
7
54
7
0
0
14
0
0
0
0
0
0
% K
% Leu:
54
14
7
20
7
47
0
0
7
14
7
20
7
14
27
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
7
7
7
% M
% Asn:
0
0
40
0
0
7
7
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
7
0
47
7
0
0
7
0
0
7
0
% P
% Gln:
0
7
7
0
7
7
0
7
0
0
0
0
0
0
14
% Q
% Arg:
0
0
0
0
7
7
7
7
0
7
0
7
0
7
0
% R
% Ser:
7
7
7
40
0
0
0
40
40
0
0
7
40
0
0
% S
% Thr:
0
0
0
0
7
0
0
0
0
7
0
0
7
0
0
% T
% Val:
14
0
0
14
7
0
20
0
14
0
7
0
7
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
0
7
7
0
0
0
0
47
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _