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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3C
All Species:
18.48
Human Site:
S380
Identified Species:
29.05
UniProt:
Q15386
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15386
NP_055486.2
1083
123923
S380
E
E
A
D
K
P
S
S
P
E
D
G
R
L
S
Chimpanzee
Pan troglodytes
XP_528010
1089
124652
S386
E
E
A
D
K
P
S
S
P
E
D
G
R
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539937
1088
124202
S384
E
E
A
D
K
Q
P
S
A
P
E
D
G
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80U95
1083
123957
S380
E
E
T
D
Q
P
N
S
P
E
D
G
R
V
S
Rat
Rattus norvegicus
Q62940
887
102376
R255
L
P
P
G
W
E
E
R
Q
D
V
L
G
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510756
1084
124281
T380
E
E
I
D
R
T
M
T
T
S
G
D
G
R
I
Chicken
Gallus gallus
NP_001026138
1084
124128
T380
E
E
I
S
K
M
T
T
T
P
G
D
G
R
I
Frog
Xenopus laevis
Q6DCL5
944
106566
S312
K
L
L
S
I
S
S
S
Y
E
A
Q
M
K
S
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
V133
D
T
V
R
G
Q
I
V
V
S
L
Q
S
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611896
1122
128925
R414
D
E
E
L
P
A
A
R
T
L
D
Y
D
M
E
Honey Bee
Apis mellifera
XP_396547
1033
119022
V372
V
Q
G
I
L
L
A
V
D
R
S
K
D
P
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797123
1037
118587
T378
V
Q
C
L
I
A
T
T
T
H
G
N
V
A
A
Poplar Tree
Populus trichocarpa
XP_002314972
1027
117409
S368
E
A
L
P
P
I
K
S
S
S
S
T
M
D
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWB8
1029
117643
S369
T
L
P
P
V
K
S
S
E
G
E
S
R
Q
G
Baker's Yeast
Sacchar. cerevisiae
P53119
910
105547
V278
E
K
A
F
I
D
E
V
I
A
T
T
A
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
N.A.
95.4
N.A.
93.3
22.1
N.A.
91.4
90.6
22.8
22.5
N.A.
39.7
43
N.A.
44.2
Protein Similarity:
100
98.1
N.A.
97.4
N.A.
97.2
38.4
N.A.
95.6
94.8
39
38.3
N.A.
61
62.7
N.A.
61.6
P-Site Identity:
100
100
N.A.
40
N.A.
73.3
0
N.A.
20
20
26.6
0
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
100
N.A.
46.6
N.A.
93.3
13.3
N.A.
33.3
33.3
33.3
6.6
N.A.
33.3
20
N.A.
26.6
Percent
Protein Identity:
28.3
N.A.
N.A.
28.7
26.7
N.A.
Protein Similarity:
47
N.A.
N.A.
49
44.9
N.A.
P-Site Identity:
13.3
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
27
0
0
14
14
0
7
7
7
0
7
7
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
0
34
0
7
0
0
7
7
27
20
14
7
7
% D
% Glu:
54
47
7
0
0
7
14
0
7
27
14
0
0
0
14
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
7
7
0
0
0
0
7
20
20
27
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
14
7
20
7
7
0
7
0
0
0
0
0
14
% I
% Lys:
7
7
0
0
27
7
7
0
0
0
0
7
0
7
0
% K
% Leu:
7
14
14
14
7
7
0
0
0
7
7
7
0
14
7
% L
% Met:
0
0
0
0
0
7
7
0
0
0
0
0
14
7
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
0
7
0
7
0
% N
% Pro:
0
7
14
14
14
20
7
0
20
14
0
0
0
7
0
% P
% Gln:
0
14
0
0
7
14
0
0
7
0
0
14
0
7
0
% Q
% Arg:
0
0
0
7
7
0
0
14
0
7
0
0
27
34
0
% R
% Ser:
0
0
0
14
0
7
27
47
7
20
14
7
7
0
34
% S
% Thr:
7
7
7
0
0
7
14
20
27
0
7
14
0
0
7
% T
% Val:
14
0
7
0
7
0
0
20
7
0
7
0
7
7
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _