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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3C All Species: 12.42
Human Site: S387 Identified Species: 19.52
UniProt: Q15386 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15386 NP_055486.2 1083 123923 S387 S P E D G R L S V S Y I T E E
Chimpanzee Pan troglodytes XP_528010 1089 124652 S393 S P E D G R L S V S Y I T E E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539937 1088 124202 L391 S A P E D G R L S V P Y I T E
Cat Felis silvestris
Mouse Mus musculus Q80U95 1083 123957 S387 S P E D G R V S A P Y I T E E
Rat Rattus norvegicus Q62940 887 102376 T262 R Q D V L G R T Y Y V N H E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510756 1084 124281 I387 T T S G D G R I S I Q Y I T E
Chicken Gallus gallus NP_001026138 1084 124128 I387 T T P G D G R I S V Q Y I T E
Frog Xenopus laevis Q6DCL5 944 106566 S319 S Y E A Q M K S L L R I V R I
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 D140 V V S L Q S R D R I G S G G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611896 1122 128925 E421 R T L D Y D M E Q T C R T S G
Honey Bee Apis mellifera XP_396547 1033 119022 S379 V D R S K D P S V L Q P L C Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797123 1037 118587 A385 T T H G N V A A L T A L C T L
Poplar Tree Populus trichocarpa XP_002314972 1027 117409 E375 S S S S T M D E D D M A L P D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWB8 1029 117643 G376 S E G E S R Q G S S D E D D M
Baker's Yeast Sacchar. cerevisiae P53119 910 105547 Y285 V I A T T A N Y V S D E D H V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 N.A. 95.4 N.A. 93.3 22.1 N.A. 91.4 90.6 22.8 22.5 N.A. 39.7 43 N.A. 44.2
Protein Similarity: 100 98.1 N.A. 97.4 N.A. 97.2 38.4 N.A. 95.6 94.8 39 38.3 N.A. 61 62.7 N.A. 61.6
P-Site Identity: 100 100 N.A. 13.3 N.A. 80 6.6 N.A. 6.6 6.6 26.6 0 N.A. 13.3 13.3 N.A. 0
P-Site Similarity: 100 100 N.A. 20 N.A. 86.6 20 N.A. 13.3 13.3 33.3 0 N.A. 26.6 20 N.A. 33.3
Percent
Protein Identity: 28.3 N.A. N.A. 28.7 26.7 N.A.
Protein Similarity: 47 N.A. N.A. 49 44.9 N.A.
P-Site Identity: 6.6 N.A. N.A. 20 13.3 N.A.
P-Site Similarity: 13.3 N.A. N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 7 0 7 7 7 7 0 7 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 7 0 7 7 0 % C
% Asp: 0 7 7 27 20 14 7 7 7 7 14 0 14 7 7 % D
% Glu: 0 7 27 14 0 0 0 14 0 0 0 14 0 27 40 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 20 20 27 0 7 0 0 7 0 7 7 7 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 7 7 0 % H
% Ile: 0 7 0 0 0 0 0 14 0 14 0 27 20 0 7 % I
% Lys: 0 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 7 7 7 0 14 7 14 14 0 7 14 0 7 % L
% Met: 0 0 0 0 0 14 7 0 0 0 7 0 0 0 7 % M
% Asn: 0 0 0 0 7 0 7 0 0 0 0 7 0 0 0 % N
% Pro: 0 20 14 0 0 0 7 0 0 7 7 7 0 7 7 % P
% Gln: 0 7 0 0 14 0 7 0 7 0 20 0 0 0 7 % Q
% Arg: 14 0 7 0 0 27 34 0 7 0 7 7 0 7 0 % R
% Ser: 47 7 20 14 7 7 0 34 27 27 0 7 0 7 7 % S
% Thr: 20 27 0 7 14 0 0 7 0 14 0 0 27 27 0 % T
% Val: 20 7 0 7 0 7 7 0 27 14 7 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 0 0 7 7 7 20 20 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _