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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3C
All Species:
9.7
Human Site:
S418
Identified Species:
15.24
UniProt:
Q15386
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15386
NP_055486.2
1083
123923
S418
L
V
W
R
D
S
A
S
E
E
V
F
T
T
M
Chimpanzee
Pan troglodytes
XP_528010
1089
124652
S424
L
V
W
R
D
S
A
S
E
E
V
F
T
T
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539937
1088
124202
A422
N
L
V
W
R
D
S
A
S
E
E
A
L
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80U95
1083
123957
S418
L
V
W
R
D
S
A
S
E
E
V
F
T
R
M
Rat
Rattus norvegicus
Q62940
887
102376
L293
D
E
N
G
D
I
Q
L
Q
A
H
G
A
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510756
1084
124281
A418
N
M
V
W
R
D
S
A
S
E
E
V
F
T
L
Chicken
Gallus gallus
NP_001026138
1084
124128
A418
N
M
V
W
R
D
S
A
S
E
E
V
F
T
L
Frog
Xenopus laevis
Q6DCL5
944
106566
K350
D
M
G
Y
N
G
N
K
T
P
R
N
Q
V
F
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
G171
E
E
R
R
T
A
S
G
R
I
Q
Y
L
N
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611896
1122
128925
D452
L
N
E
T
E
R
V
D
F
I
V
Q
Q
L
D
Honey Bee
Apis mellifera
XP_396547
1033
119022
F410
K
L
L
Y
M
L
A
F
K
P
I
F
L
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797123
1037
118587
N416
L
L
Y
S
L
A
I
N
K
S
F
L
R
H
L
Poplar Tree
Populus trichocarpa
XP_002314972
1027
117409
L406
A
M
H
S
R
F
L
L
Q
L
T
S
V
L
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWB8
1029
117643
S407
Q
I
T
N
A
I
D
S
R
F
L
L
Q
L
T
Baker's Yeast
Sacchar. cerevisiae
P53119
910
105547
L316
N
S
V
L
I
T
L
L
S
N
K
D
F
V
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
N.A.
95.4
N.A.
93.3
22.1
N.A.
91.4
90.6
22.8
22.5
N.A.
39.7
43
N.A.
44.2
Protein Similarity:
100
98.1
N.A.
97.4
N.A.
97.2
38.4
N.A.
95.6
94.8
39
38.3
N.A.
61
62.7
N.A.
61.6
P-Site Identity:
100
100
N.A.
13.3
N.A.
93.3
6.6
N.A.
13.3
13.3
0
6.6
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
100
N.A.
40
N.A.
93.3
13.3
N.A.
40
40
13.3
26.6
N.A.
20
33.3
N.A.
46.6
Percent
Protein Identity:
28.3
N.A.
N.A.
28.7
26.7
N.A.
Protein Similarity:
47
N.A.
N.A.
49
44.9
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
14
27
20
0
7
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
0
0
27
20
7
7
0
0
0
7
0
0
7
% D
% Glu:
7
14
7
0
7
0
0
0
20
40
20
0
0
0
0
% E
% Phe:
0
0
0
0
0
7
0
7
7
7
7
27
20
7
14
% F
% Gly:
0
0
7
7
0
7
0
7
0
0
0
7
0
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
7
0
0
7
7
% H
% Ile:
0
7
0
0
7
14
7
0
0
14
7
0
0
0
0
% I
% Lys:
7
0
0
0
0
0
0
7
14
0
7
0
0
7
0
% K
% Leu:
34
20
7
7
7
7
14
20
0
7
7
14
20
20
27
% L
% Met:
0
27
0
0
7
0
0
0
0
0
0
0
0
0
20
% M
% Asn:
27
7
7
7
7
0
7
7
0
7
0
7
0
7
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
7
0
14
0
7
7
20
0
0
% Q
% Arg:
0
0
7
27
27
7
0
0
14
0
7
0
7
7
7
% R
% Ser:
0
7
0
14
0
20
27
27
27
7
0
7
0
0
0
% S
% Thr:
0
0
7
7
7
7
0
0
7
0
7
0
20
34
14
% T
% Val:
0
20
27
0
0
0
7
0
0
0
27
14
7
14
0
% V
% Trp:
0
0
20
20
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
14
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _