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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3C
All Species:
23.03
Human Site:
S489
Identified Species:
36.19
UniProt:
Q15386
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15386
NP_055486.2
1083
123923
S489
I
S
R
G
S
P
M
S
F
E
D
S
S
R
I
Chimpanzee
Pan troglodytes
XP_528010
1089
124652
S495
I
S
R
G
S
P
M
S
F
E
D
S
S
R
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539937
1088
124202
S494
I
S
R
G
S
P
M
S
L
E
D
S
S
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q80U95
1083
123957
S489
I
S
R
G
S
P
M
S
F
E
D
S
S
R
I
Rat
Rattus norvegicus
Q62940
887
102376
Y362
L
D
T
R
L
T
M
Y
G
N
P
A
T
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510756
1084
124281
S490
I
S
R
G
S
P
M
S
L
E
D
S
S
R
I
Chicken
Gallus gallus
NP_001026138
1084
124128
S490
I
S
R
G
S
P
M
S
L
D
E
S
S
R
I
Frog
Xenopus laevis
Q6DCL5
944
106566
N419
K
N
K
R
D
S
S
N
I
A
C
I
L
L
K
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
N240
V
R
S
Q
R
H
R
N
Y
M
S
R
T
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611896
1122
128925
G535
G
V
V
P
K
H
Q
G
V
D
R
T
I
P
L
Honey Bee
Apis mellifera
XP_396547
1033
119022
Q483
T
E
F
F
I
Q
D
Q
S
L
D
I
N
G
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797123
1037
118587
D486
H
D
S
E
F
Y
G
D
D
A
D
S
N
R
N
Poplar Tree
Populus trichocarpa
XP_002314972
1027
117409
N477
F
M
K
Q
C
H
E
N
K
K
W
P
S
L
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWB8
1029
117643
R476
V
L
W
N
Y
M
K
R
C
H
E
N
Q
K
W
Baker's Yeast
Sacchar. cerevisiae
P53119
910
105547
D385
K
F
T
S
T
L
K
D
F
T
F
R
Q
Y
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
N.A.
95.4
N.A.
93.3
22.1
N.A.
91.4
90.6
22.8
22.5
N.A.
39.7
43
N.A.
44.2
Protein Similarity:
100
98.1
N.A.
97.4
N.A.
97.2
38.4
N.A.
95.6
94.8
39
38.3
N.A.
61
62.7
N.A.
61.6
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
6.6
N.A.
93.3
80
0
0
N.A.
0
6.6
N.A.
20
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
26.6
N.A.
93.3
93.3
20
33.3
N.A.
20
13.3
N.A.
26.6
Percent
Protein Identity:
28.3
N.A.
N.A.
28.7
26.7
N.A.
Protein Similarity:
47
N.A.
N.A.
49
44.9
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
14
0
7
0
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
7
0
7
0
0
0
0
% C
% Asp:
0
14
0
0
7
0
7
14
7
14
47
0
0
0
0
% D
% Glu:
0
7
0
7
0
0
7
0
0
34
14
0
0
0
0
% E
% Phe:
7
7
7
7
7
0
0
0
27
0
7
0
0
0
0
% F
% Gly:
7
0
0
40
0
0
7
7
7
0
0
0
0
7
0
% G
% His:
7
0
0
0
0
20
0
0
0
7
0
0
0
7
0
% H
% Ile:
40
0
0
0
7
0
0
0
7
0
0
14
7
0
40
% I
% Lys:
14
0
14
0
7
0
14
0
7
7
0
0
0
7
7
% K
% Leu:
7
7
0
0
7
7
0
0
20
7
0
0
7
14
14
% L
% Met:
0
7
0
0
0
7
47
0
0
7
0
0
0
0
0
% M
% Asn:
0
7
0
7
0
0
0
20
0
7
0
7
14
0
7
% N
% Pro:
0
0
0
7
0
40
0
0
0
0
7
7
0
7
7
% P
% Gln:
0
0
0
14
0
7
7
7
0
0
0
0
14
0
14
% Q
% Arg:
0
7
40
14
7
0
7
7
0
0
7
14
0
47
0
% R
% Ser:
0
40
14
7
40
7
7
40
7
0
7
47
47
7
0
% S
% Thr:
7
0
14
0
7
7
0
0
0
7
0
7
14
0
0
% T
% Val:
14
7
7
0
0
0
0
0
7
0
0
0
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
14
% W
% Tyr:
0
0
0
0
7
7
0
7
7
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _