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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3C All Species: 13.33
Human Site: S672 Identified Species: 20.95
UniProt: Q15386 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15386 NP_055486.2 1083 123923 S672 T L D V G L E S P P L S V S E
Chimpanzee Pan troglodytes XP_528010 1089 124652 S678 T L D V G L E S P P L S V S E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539937 1088 124202 S677 S L D V G L E S P P L S V S E
Cat Felis silvestris
Mouse Mus musculus Q80U95 1083 123957 S672 T L E V G L E S L P L S V S E
Rat Rattus norvegicus Q62940 887 102376 L533 P N K F E M K L R R A N I L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510756 1084 124281 P673 T L D V G L E P A P L S V S E
Chicken Gallus gallus NP_001026138 1084 124128 P673 T L D V G L E P A P L S V S E
Frog Xenopus laevis Q6DCL5 944 106566 L590 P V N E N D I L L V H R D S I
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 R411 Q P Q A G H C R I E V S R E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611896 1122 128925 G710 T R E D F E N G P P M S T K Q
Honey Bee Apis mellifera XP_396547 1033 119022 L654 R V V A F Q S L I Y R D K T E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797123 1037 118587 W661 R V Q V F R D W V L A D K H D
Poplar Tree Populus trichocarpa XP_002314972 1027 117409 Q648 R V K I F N S Q L L A I R Q R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWB8 1029 117643 Q650 R V K I F T T Q L A T A R Q S
Baker's Yeast Sacchar. cerevisiae P53119 910 105547 A556 T G M R K Q S A I I S R D N V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 N.A. 95.4 N.A. 93.3 22.1 N.A. 91.4 90.6 22.8 22.5 N.A. 39.7 43 N.A. 44.2
Protein Similarity: 100 98.1 N.A. 97.4 N.A. 97.2 38.4 N.A. 95.6 94.8 39 38.3 N.A. 61 62.7 N.A. 61.6
P-Site Identity: 100 100 N.A. 93.3 N.A. 86.6 6.6 N.A. 86.6 86.6 6.6 20 N.A. 26.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 33.3 N.A. 86.6 86.6 20 26.6 N.A. 46.6 20 N.A. 26.6
Percent
Protein Identity: 28.3 N.A. N.A. 28.7 26.7 N.A.
Protein Similarity: 47 N.A. N.A. 49 44.9 N.A.
P-Site Identity: 0 N.A. N.A. 0 6.6 N.A.
P-Site Similarity: 13.3 N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 0 0 0 7 14 7 20 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 34 7 0 7 7 0 0 0 0 14 14 0 7 % D
% Glu: 0 0 14 7 7 7 40 0 0 7 0 0 0 7 60 % E
% Phe: 0 0 0 7 34 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 0 47 0 0 7 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 7 0 0 0 0 7 0 0 7 0 % H
% Ile: 0 0 0 14 0 0 7 0 20 7 0 7 7 0 7 % I
% Lys: 0 0 20 0 7 0 7 0 0 0 0 0 14 7 0 % K
% Leu: 0 40 0 0 0 40 0 20 27 14 40 0 0 7 0 % L
% Met: 0 0 7 0 0 7 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 7 7 0 7 7 7 0 0 0 0 7 0 7 0 % N
% Pro: 14 7 0 0 0 0 0 14 27 47 0 0 0 0 0 % P
% Gln: 7 0 14 0 0 14 0 14 0 0 0 0 0 14 7 % Q
% Arg: 27 7 0 7 0 7 0 7 7 7 7 14 20 0 7 % R
% Ser: 7 0 0 0 0 0 20 27 0 0 7 54 0 47 7 % S
% Thr: 47 0 0 0 0 7 7 0 0 0 7 0 7 7 0 % T
% Val: 0 34 7 47 0 0 0 0 7 7 7 0 40 0 7 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _