Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3C All Species: 24.85
Human Site: S676 Identified Species: 39.05
UniProt: Q15386 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15386 NP_055486.2 1083 123923 S676 G L E S P P L S V S E E R Q L
Chimpanzee Pan troglodytes XP_528010 1089 124652 S682 G L E S P P L S V S E E R Q L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539937 1088 124202 S681 G L E S P P L S V S E E R Q L
Cat Felis silvestris
Mouse Mus musculus Q80U95 1083 123957 S676 G L E S L P L S V S E E R Q L
Rat Rattus norvegicus Q62940 887 102376 N537 E M K L R R A N I L E D S Y R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510756 1084 124281 S677 G L E P A P L S V S E E R Q L
Chicken Gallus gallus NP_001026138 1084 124128 S677 G L E P A P L S V S E E R Q L
Frog Xenopus laevis Q6DCL5 944 106566 R594 N D I L L V H R D S I F R S S
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 S415 G H C R I E V S R E E I F E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611896 1122 128925 S714 F E N G P P M S T K Q I R S I
Honey Bee Apis mellifera XP_396547 1033 119022 D658 F Q S L I Y R D K T E Q Q G E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797123 1037 118587 D665 F R D W V L A D K H D S Q G E
Poplar Tree Populus trichocarpa XP_002314972 1027 117409 I652 F N S Q L L A I R Q R Q G S H
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWB8 1029 117643 A654 F T T Q L A T A R Q S H G S Q
Baker's Yeast Sacchar. cerevisiae P53119 910 105547 R560 K Q S A I I S R D N V L E D A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 N.A. 95.4 N.A. 93.3 22.1 N.A. 91.4 90.6 22.8 22.5 N.A. 39.7 43 N.A. 44.2
Protein Similarity: 100 98.1 N.A. 97.4 N.A. 97.2 38.4 N.A. 95.6 94.8 39 38.3 N.A. 61 62.7 N.A. 61.6
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 6.6 N.A. 86.6 86.6 13.3 20 N.A. 26.6 6.6 N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 40 N.A. 86.6 86.6 13.3 33.3 N.A. 46.6 26.6 N.A. 20
Percent
Protein Identity: 28.3 N.A. N.A. 28.7 26.7 N.A.
Protein Similarity: 47 N.A. N.A. 49 44.9 N.A.
P-Site Identity: 0 N.A. N.A. 0 0 N.A.
P-Site Similarity: 6.6 N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 14 7 20 7 0 0 0 0 0 0 7 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 0 0 0 0 14 14 0 7 7 0 7 0 % D
% Glu: 7 7 40 0 0 7 0 0 0 7 60 40 7 7 20 % E
% Phe: 34 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % F
% Gly: 47 0 0 7 0 0 0 0 0 0 0 0 14 14 0 % G
% His: 0 7 0 0 0 0 7 0 0 7 0 7 0 0 7 % H
% Ile: 0 0 7 0 20 7 0 7 7 0 7 14 0 0 7 % I
% Lys: 7 0 7 0 0 0 0 0 14 7 0 0 0 0 0 % K
% Leu: 0 40 0 20 27 14 40 0 0 7 0 7 0 0 40 % L
% Met: 0 7 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 7 7 7 0 0 0 0 7 0 7 0 0 0 0 0 % N
% Pro: 0 0 0 14 27 47 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 14 0 14 0 0 0 0 0 14 7 14 14 40 7 % Q
% Arg: 0 7 0 7 7 7 7 14 20 0 7 0 54 0 7 % R
% Ser: 0 0 20 27 0 0 7 54 0 47 7 7 7 27 7 % S
% Thr: 0 7 7 0 0 0 7 0 7 7 0 0 0 0 0 % T
% Val: 0 0 0 0 7 7 7 0 40 0 7 0 0 0 0 % V
% Trp: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _