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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3C All Species: 27.58
Human Site: S875 Identified Species: 43.33
UniProt: Q15386 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15386 NP_055486.2 1083 123923 S875 K N L L F L K S Y E D D V E E
Chimpanzee Pan troglodytes XP_528010 1089 124652 S881 K N L L F L K S Y E D D V E E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539937 1088 124202 S880 K N L L F L K S Y E G D V E E
Cat Felis silvestris
Mouse Mus musculus Q80U95 1083 123957 S875 R N L L F L K S Y E E D V E E
Rat Rattus norvegicus Q62940 887 102376 H700 L F G Q T H Q H E L K T G G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510756 1084 124281 S876 K N L L F L K S Y E D D V E E
Chicken Gallus gallus NP_001026138 1084 124128 S876 K N L L F L K S Y E G D V E E
Frog Xenopus laevis Q6DCL5 944 106566 P757 F G A M E E V P L K P G G A S
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 Q578 N A Y G E I I Q H E L K P N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611896 1122 128925 D915 R N L L Y L K D Y S G D V S E
Honey Bee Apis mellifera XP_396547 1033 119022 S826 R N L L Y L K S Y K G D V A D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797123 1037 118587 Q833 K D Y K S W S Q I Y R I P T E
Poplar Tree Populus trichocarpa XP_002314972 1027 117409 Q816 L I F L K R Y Q G D I S D L E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWB8 1029 117643 K818 L I F L K R Y K G D I S D L E
Baker's Yeast Sacchar. cerevisiae P53119 910 105547 S723 F E I D E P E S S A K V V D L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 N.A. 95.4 N.A. 93.3 22.1 N.A. 91.4 90.6 22.8 22.5 N.A. 39.7 43 N.A. 44.2
Protein Similarity: 100 98.1 N.A. 97.4 N.A. 97.2 38.4 N.A. 95.6 94.8 39 38.3 N.A. 61 62.7 N.A. 61.6
P-Site Identity: 100 100 N.A. 93.3 N.A. 86.6 0 N.A. 100 93.3 0 6.6 N.A. 60 60 N.A. 13.3
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 6.6 N.A. 100 93.3 13.3 20 N.A. 73.3 86.6 N.A. 20
Percent
Protein Identity: 28.3 N.A. N.A. 28.7 26.7 N.A.
Protein Similarity: 47 N.A. N.A. 49 44.9 N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: 20 N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 0 0 0 0 0 7 0 0 0 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 7 0 0 0 7 0 14 20 54 14 7 7 % D
% Glu: 0 7 0 0 20 7 7 0 7 47 7 0 0 40 67 % E
% Phe: 14 7 14 0 40 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 7 7 0 0 0 0 14 0 27 7 14 7 7 % G
% His: 0 0 0 0 0 7 0 7 7 0 0 0 0 0 0 % H
% Ile: 0 14 7 0 0 7 7 0 7 0 14 7 0 0 0 % I
% Lys: 40 0 0 7 14 0 54 7 0 14 14 7 0 0 0 % K
% Leu: 20 0 54 67 0 54 0 0 7 7 7 0 0 14 7 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 54 0 0 0 0 0 0 0 0 0 0 0 7 0 % N
% Pro: 0 0 0 0 0 7 0 7 0 0 7 0 14 0 0 % P
% Gln: 0 0 0 7 0 0 7 20 0 0 0 0 0 0 0 % Q
% Arg: 20 0 0 0 0 14 0 0 0 0 7 0 0 0 0 % R
% Ser: 0 0 0 0 7 0 7 54 7 7 0 14 0 7 14 % S
% Thr: 0 0 0 0 7 0 0 0 0 0 0 7 0 7 0 % T
% Val: 0 0 0 0 0 0 7 0 0 0 0 7 60 0 0 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 14 0 14 0 14 0 54 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _