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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3C All Species: 23.03
Human Site: S972 Identified Species: 36.19
UniProt: Q15386 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15386 NP_055486.2 1083 123923 S972 S G A Q V P I S L E D L K S F
Chimpanzee Pan troglodytes XP_528010 1089 124652 S978 S G A Q V P I S L E D L K S F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539937 1088 124202 S977 S G A Q V P I S L E D L K S F
Cat Felis silvestris
Mouse Mus musculus Q80U95 1083 123957 S972 S G A Q V P V S L E D L K S F
Rat Rattus norvegicus Q62940 887 102376 T779 V N D W R E H T K Y K N G Y S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510756 1084 124281 S973 S G A Q V P I S L D D L K S F
Chicken Gallus gallus NP_001026138 1084 124128 S973 S G A Q V P I S L D D L K S F
Frog Xenopus laevis Q6DCL5 944 106566 E836 N D W M K N T E Y T S G Y E R
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 N657 D I N D W K S N T R L K H C T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611896 1122 128925 D1012 S G A E I P I D L E D L K K H
Honey Bee Apis mellifera XP_396547 1033 119022 D923 S G A Q I P V D V N D L K L H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797123 1037 118587 D926 S G A S M P I D V E D L R Q H
Poplar Tree Populus trichocarpa XP_002314972 1027 117409 D911 S G S L D S L D I D D L R S H
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWB8 1029 117643 D913 S G S V D S L D I D D L R N N
Baker's Yeast Sacchar. cerevisiae P53119 910 105547 D802 E R D N I D L D D L K S N T E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 N.A. 95.4 N.A. 93.3 22.1 N.A. 91.4 90.6 22.8 22.5 N.A. 39.7 43 N.A. 44.2
Protein Similarity: 100 98.1 N.A. 97.4 N.A. 97.2 38.4 N.A. 95.6 94.8 39 38.3 N.A. 61 62.7 N.A. 61.6
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 0 N.A. 93.3 93.3 0 0 N.A. 66.6 53.3 N.A. 53.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 6.6 N.A. 100 100 6.6 6.6 N.A. 80 73.3 N.A. 73.3
Percent
Protein Identity: 28.3 N.A. N.A. 28.7 26.7 N.A.
Protein Similarity: 47 N.A. N.A. 49 44.9 N.A.
P-Site Identity: 33.3 N.A. N.A. 26.6 0 N.A.
P-Site Similarity: 66.6 N.A. N.A. 66.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 60 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 7 7 14 7 14 7 0 40 7 27 74 0 0 0 0 % D
% Glu: 7 0 0 7 0 7 0 7 0 40 0 0 0 7 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 40 % F
% Gly: 0 74 0 0 0 0 0 0 0 0 0 7 7 0 0 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 27 % H
% Ile: 0 7 0 0 20 0 47 0 14 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 7 7 0 0 7 0 14 7 54 7 0 % K
% Leu: 0 0 0 7 0 0 20 0 47 7 7 74 0 7 0 % L
% Met: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 7 7 7 0 7 0 7 0 7 0 7 7 7 7 % N
% Pro: 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 47 0 0 0 0 0 0 0 0 0 7 0 % Q
% Arg: 0 7 0 0 7 0 0 0 0 7 0 0 20 0 7 % R
% Ser: 74 0 14 7 0 14 7 40 0 0 7 7 0 47 7 % S
% Thr: 0 0 0 0 0 0 7 7 7 7 0 0 0 7 7 % T
% Val: 7 0 0 7 40 0 14 0 14 0 0 0 0 0 0 % V
% Trp: 0 0 7 7 7 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 7 0 0 7 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _